FA98A_MOUSE - dbPTM
FA98A_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FA98A_MOUSE
UniProt AC Q3TJZ6
Protein Name Protein FAM98A
Gene Name Fam98a
Organism Mus musculus (Mouse).
Sequence Length 515
Subcellular Localization
Protein Description Positively stimulates PRMT1-induced protein arginine methylation (By similarity). Involved in skeletal homeostasis. [PubMed: 27777970 Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts]
Protein Sequence MECDLMETDILESLEDLGYKGPLLDDGALLQAVSAGAASPEFTKLCAWLVSELRVLCKLEENVQATNSPSEAEEFQLEVSGLLGEMNCPYPSLTSGDVTKRLLVEKNCLLLLTYLISELEAARMLCVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTDKLAKVYQPKRSLLSPKGKVSVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQAGGRGGGRGGYEHSSYGGRGGHEQGGRGGRGSYDHGGRGGGRGNKHQGGWTDGGSGSGGGYQDGAYRDSGFQPGGYHGGHSGGYQAGGYGGFQTSSYTGSGYQGGGYQQDNRYQDGGHHGERGSGRGGRGGRGGRGGRGSQGGGWGGRGSQTYHQGGQFEQHFQHGGYQYSHSGFGQGRHYTS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
44UbiquitinationAASPEFTKLCAWLVS
CCCHHHHHHHHHHHH		47.06-
46S-palmitoylationSPEFTKLCAWLVSEL
CHHHHHHHHHHHHHH		2.4528526873
53UbiquitinationCAWLVSELRVLCKLE
HHHHHHHHHHHHHHH		3.4127667366
189UbiquitinationVPPNHVGKPLLKKPM
CCCCCCCCCCCCCCC		31.2527667366
203AcetylationMGPAHWEKIEAINQA
CCHHHHHHHHHHHHH		40.437623965
245AcetylationRAKSQTDKLAKVYQP
HHHHHHHHHHHHHCC		54.452382907
248UbiquitinationSQTDKLAKVYQPKRS
HHHHHHHHHHCCCHH		52.4927667366
255PhosphorylationKVYQPKRSLLSPKGK
HHHCCCHHHCCCCCC		39.5324719451
258PhosphorylationQPKRSLLSPKGKVSV
CCCHHHCCCCCCCCH		29.8324453211
282PhosphorylationLSKILRTSSGSIREK
HHHHHHHCCCCHHHH		26.6929514104
283PhosphorylationSKILRTSSGSIREKT
HHHHHHCCCCHHHHH		35.6329514104
285PhosphorylationILRTSSGSIREKTAC
HHHHCCCCHHHHHHH		22.0323684622
292GlutathionylationSIREKTACAINKVLM
CHHHHHHHHHHHHHC		4.7724333276
296UbiquitinationKTACAINKVLMGRVP
HHHHHHHHHHCCCCC		30.54-
296AcetylationKTACAINKVLMGRVP
HHHHHHHHHHCCCCC		30.5422826441
336MethylationPQQQAGGRGGGRGGY
CCCCCCCCCCCCCCC		39.40-
383PhosphorylationNKHQGGWTDGGSGSG
CCCCCCCCCCCCCCC		28.2123684622
387PhosphorylationGGWTDGGSGSGGGYQ
CCCCCCCCCCCCCCC		35.0023684622
389PhosphorylationWTDGGSGSGGGYQDG
CCCCCCCCCCCCCCC		35.6423684622
514PhosphorylationFGQGRHYTS------
CCCCCCCCC------		23.10-
515PhosphorylationGQGRHYTS-------
CCCCCCCC-------		30.93-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FA98A_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FA98A_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FA98A_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of FA98A_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FA98A_MOUSE

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Related Literatures of Post-Translational Modification

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