FA83F_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA83F_HUMAN
• UniProt AC: Q8NEG4
• Protein Name: Protein FAM83F
• Gene Name: FAM83F
• Organism: Homo sapiens (Human).
• Sequence Length: 500
• Protein Sequence: MAESQLNCLDEAHVNEKVTEAQAAFYYCERRRAALEALLGGGEQAYRERLKEEQLRDFLSSPERQALRAAWSPYEDAVPAANARGKSKAKAKAPAPAPAESGESLAYWPDRSDTEVPPLDLGWTDTGFYRGVSRVTLFTHPPKDEKAPHLKQVVRQMIQQAQKVIAVVMDLFTDGDIFQDIVDAACKRRVPVYIILDEAGVKYFLEMCQDLQLTDFRIRNIRVRSVTGVGFYMPMGRIKGTLSSRFLMVDGDKVATGSYRFTWSSSHVDRNLLLLLTGQNVEPFDTEFRELYAISEEVDLYRQLSLAGRVGLHYSSTVARKLINPKYALVSGCRHPPGEMMRWAARQQREAGGNPEGQEEGASGGESAWRLESFLKDLVTVEQVLPPVEPIPLGELSQKDGRMVSHMHRDLKPKSREAPSRNGMGEAARGEAAPARRFSSRLFSRRAKRPAAPNGMASSVSTETSEVEFLTGKRPNENSSADISGKTSPSSAKPSNCVIS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAESQLNCL ------CCHHHHHHC	25.75	21406692
4	Phosphorylation	----MAESQLNCLDE ----CCHHHHHHCCH	30.35	28355574
26	Phosphorylation	TEAQAAFYYCERRRA HHHHHHHHHHHHHHH	11.50	24260401
27	Phosphorylation	EAQAAFYYCERRRAA HHHHHHHHHHHHHHH	4.95	24260401
60	Phosphorylation	EQLRDFLSSPERQAL HHHHHHHHCHHHHHH	43.79	25056879
61	Phosphorylation	QLRDFLSSPERQALR HHHHHHHCHHHHHHH	32.69	29496963
72	Phosphorylation	QALRAAWSPYEDAVP HHHHHHCCCHHHHHC	16.93	24719451
74	Phosphorylation	LRAAWSPYEDAVPAA HHHHCCCHHHHHCHH	22.41	27642862
87	Phosphorylation	AANARGKSKAKAKAP HHHHCCCCCCCCCCC	40.44	-
101	Phosphorylation	PAPAPAESGESLAYW CCCCCCCCCCCCCCC	50.39	26657352
104	Phosphorylation	APAESGESLAYWPDR CCCCCCCCCCCCCCC	23.09	28152594
107	Phosphorylation	ESGESLAYWPDRSDT CCCCCCCCCCCCCCC	23.83	28152594
112	Phosphorylation	LAYWPDRSDTEVPPL CCCCCCCCCCCCCCC	57.15	27259358
114	Phosphorylation	YWPDRSDTEVPPLDL CCCCCCCCCCCCCCC	39.88	26356563
129	Phosphorylation	GWTDTGFYRGVSRVT CCCCCCCCCCCCEEE	14.06	22817900
203	Phosphorylation	LDEAGVKYFLEMCQD ECHHHHHHHHHHHCC	15.81	-
231 (in isoform 2)	Ubiquitination	-	4.37	21906983
253	Ubiquitination	FLMVDGDKVATGSYR EEEECCCEEEEEEEE	39.02	-
305	Phosphorylation	VDLYRQLSLAGRVGL HHHHHHHHHHCCCCC	14.08	24719451
314	Phosphorylation	AGRVGLHYSSTVARK HCCCCCCCCHHHHHH	14.90	26356563
315	Phosphorylation	GRVGLHYSSTVARKL CCCCCCCCHHHHHHH	14.58	26356563
316	Phosphorylation	RVGLHYSSTVARKLI CCCCCCCHHHHHHHC	21.53	28857561
317	Phosphorylation	VGLHYSSTVARKLIN CCCCCCHHHHHHHCC	16.55	26356563
321	Ubiquitination	YSSTVARKLINPKYA CCHHHHHHHCCCCCE	43.94	27667366
326	Ubiquitination	ARKLINPKYALVSGC HHHHCCCCCEEECCC	38.37	27667366
327	Phosphorylation	RKLINPKYALVSGCR HHHCCCCCEEECCCC	13.36	29083192
331	Phosphorylation	NPKYALVSGCRHPPG CCCCEEECCCCCCCH	32.78	27470641
363	Phosphorylation	EGQEEGASGGESAWR CCCCCCCCCCHHHHH	59.18	22210691
367	Phosphorylation	EGASGGESAWRLESF CCCCCCHHHHHHHHH	36.08	22210691
373	Phosphorylation	ESAWRLESFLKDLVT HHHHHHHHHHHHCCC	40.23	24719451
399 (in isoform 1)	Ubiquitination	-	59.79	21906983
399	Ubiquitination	PLGELSQKDGRMVSH CHHHCCCCCCCCCCH	59.79	22817900
405	Phosphorylation	QKDGRMVSHMHRDLK CCCCCCCCHHCCCCC	13.02	22210691
458	Phosphorylation	AAPNGMASSVSTETS CCCCCCCCCCCCCCC	23.52	24719451
459	Phosphorylation	APNGMASSVSTETSE CCCCCCCCCCCCCCE	15.56	27251275
461	Phosphorylation	NGMASSVSTETSEVE CCCCCCCCCCCCEEE	23.60	28348404
462	Phosphorylation	GMASSVSTETSEVEF CCCCCCCCCCCEEEE	40.92	28348404
464	Phosphorylation	ASSVSTETSEVEFLT CCCCCCCCCEEEECC	30.21	28348404
465	Phosphorylation	SSVSTETSEVEFLTG CCCCCCCCEEEECCC	33.15	28348404
479	Phosphorylation	GKRPNENSSADISGK CCCCCCCCCCCCCCC	22.26	26657352
480	Phosphorylation	KRPNENSSADISGKT CCCCCCCCCCCCCCC	41.35	25849741
484	Phosphorylation	ENSSADISGKTSPSS CCCCCCCCCCCCCCC	34.48	28985074
487	Phosphorylation	SADISGKTSPSSAKP CCCCCCCCCCCCCCC	49.77	22817900
488	Phosphorylation	ADISGKTSPSSAKPS CCCCCCCCCCCCCCC	26.69	22817900
490	Phosphorylation	ISGKTSPSSAKPSNC CCCCCCCCCCCCCCC	42.57	28102081
491	Phosphorylation	SGKTSPSSAKPSNCV CCCCCCCCCCCCCCC	43.63	28102081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA83F_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA83F_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA83F_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of FA83F_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.