FA83C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA83C_HUMAN
• UniProt AC: Q9BQN1
• Protein Name: Protein FAM83C {ECO:0000305}
• Gene Name: FAM83C {ECO:0000312|HGNC:HGNC:16121}
• Organism: Homo sapiens (Human).
• Sequence Length: 747
• Protein Description: May play a role in MAPK signaling..
• Protein Sequence: MFGGPGPGVLGAQGMAGPLRGRVEELKLPWWRESSPLVLRHSEAARLAADALLERGEAAYLRVISEERELPFLSALDVDYMTSHVRGGPELSEAQGQEASGPDRLSLLSEVTSGTYFPMASDIDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKAKNIKDLLRFLFSQAHTVVAVVMDIFTDMELLCDLMEASSRRGVPVYLLLAQEHLRHFLEMCYKMDLNGEHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVLIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCLYAESQPVEGFCGGEDPLSPRALRPPPVALAFRPDVPSPTSSLPSSTSLSSIKQSPLMGRSSYLALPGGGDCSDTGVVSSSLGPARREASGQPSLHRQLSDPNHGSPPGLYRANLGKLGAYPWSQSSPALNHNSTSPLTLAVGSPLLPRSRPLLQFHRGAPALSRFPENGLPGSQEPSPLRGRWVPGTTLETVEEKEKKASPSQSRGQLDLLVPFPRAREVGDPDSGVTPNSGPLRPGEQAPEDRRLSPSQADSQLDLLSRALGTGGAPELGSLRPGDRALEDRRLSLNQSRGQSDLLMQYPKAQGSRVPLETNSSARPARRAPDERRQTLGHSQLDLITKFGPFRGEGPGPNGLPISSPARTAGAGSGDEKRLTLGHSKLDLITKYHQLHGARQGTEPGGPKGGHLNGGNSDLVRDEKRLTLGHSKLDLITKYNKSKFKQLRSRFES

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
171	Phosphorylation	FLFSQAHTVVAVVMD HHHHHHHHHHHHHHH	21.49	-
193	Phosphorylation	LCDLMEASSRRGVPV HHHHHHHHHHCCCCH	15.86	-
194	Phosphorylation	CDLMEASSRRGVPVY HHHHHHHHHCCCCHH	32.80	-
318	Phosphorylation	CGGEDPLSPRALRPP CCCCCCCCHHHCCCC	20.09	27251275
349	Phosphorylation	LPSSTSLSSIKQSPL CCCCCCHHHHCCCCC	29.77	24719451
362	Phosphorylation	PLMGRSSYLALPGGG CCCCCCCEEECCCCC	9.39	22210691
378	Phosphorylation	CSDTGVVSSSLGPAR CCCCCCCCCCCCHHH	16.29	22210691
380	Phosphorylation	DTGVVSSSLGPARRE CCCCCCCCCCHHHHH	29.82	22210691
463	Phosphorylation	HRGAPALSRFPENGL CCCCCHHHCCCCCCC	33.70	23403867
487	Phosphorylation	RGRWVPGTTLETVEE CCCCCCCCCCHHHHH	23.34	29083192
488	Phosphorylation	GRWVPGTTLETVEEK CCCCCCCCCHHHHHH	28.63	29083192
491	Phosphorylation	VPGTTLETVEEKEKK CCCCCCHHHHHHHHC	36.01	29083192
498	Ubiquitination	TVEEKEKKASPSQSR HHHHHHHCCCCCCCC	56.01	22505724
525	Phosphorylation	REVGDPDSGVTPNSG HHCCCCCCCCCCCCC	40.32	-
547	Phosphorylation	APEDRRLSPSQADSQ CCCCCCCCHHHHHHH	22.24	21955146
549	Phosphorylation	EDRRLSPSQADSQLD CCCCCCHHHHHHHHH	34.33	21955146
553	Phosphorylation	LSPSQADSQLDLLSR CCHHHHHHHHHHHHH	35.34	21955146
559	Phosphorylation	DSQLDLLSRALGTGG HHHHHHHHHHHCCCC	23.86	21955146
572	Phosphorylation	GGAPELGSLRPGDRA CCCCCCCCCCCCCHH	33.55	24719451
586	Phosphorylation	ALEDRRLSLNQSRGQ HHHHHCCCCCCCCCC	24.38	24719451
594	Phosphorylation	LNQSRGQSDLLMQYP CCCCCCCHHHHHHCC	32.80	18452278
600	Phosphorylation	QSDLLMQYPKAQGSR CHHHHHHCCCCCCCC	7.85	-
606	Phosphorylation	QYPKAQGSRVPLETN HCCCCCCCCCCCCCC	20.30	18452278
686	Phosphorylation	KLDLITKYHQLHGAR HHHHHHHHHHHHCCC	6.02	22210691
696	Phosphorylation	LHGARQGTEPGGPKG HHCCCCCCCCCCCCC	30.57	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA83C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA83C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA83C_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of FA83C_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.