dbPTM

F1891_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	F1891_HUMAN
UniProt AC	O60320
Protein Name	Protein FAM189A1
Gene Name	FAM189A1
Organism	Homo sapiens (Human).
Sequence Length	539
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MPPAGGPRAPRPAALPRSLSRLRECPGRSRIVLALGATQMALGCLIVAVSFAALALTTSARVRHSCPFWAGFSVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQLVNSLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSVCALNVLSTIVCALATAMCCMQMVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPRSLVDSKAYADARVLVAKFLEHSHCALPTEAQHMVGAMRLAVTNEERLEEEAVFGADVLDQV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	RPAALPRSLSRLREC CCCCCCCHHHHHHCC	28.85	24702127
20	Phosphorylation	AALPRSLSRLRECPG CCCCCHHHHHHCCCC	30.43	24888630
29	Phosphorylation	LRECPGRSRIVLALG HHCCCCCHHHHHHHH	32.07	22210691
38	Phosphorylation	IVLALGATQMALGCL HHHHHHHHHHHHHHH	19.65	22210691
50	Phosphorylation	GCLIVAVSFAALALT HHHHHHHHHHHHHHH	10.22	22210691
479	Phosphorylation	TSKERPRSLVDSKAY CCCCCCHHHCCCHHH	35.11	23911959
483	Phosphorylation	RPRSLVDSKAYADAR CCHHHCCCHHHHHHH	16.23	23911959
486	Phosphorylation	SLVDSKAYADARVLV HHCCCHHHHHHHHHH	14.57	23911959

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of F1891_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of F1891_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of F1891_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of F1891_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of F1891_HUMAN

Related Literatures of Post-Translational Modification