F184B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F184B_HUMAN
• UniProt AC: Q9ULE4
• Protein Name: Protein FAM184B
• Gene Name: FAM184B
• Organism: Homo sapiens (Human).
• Sequence Length: 1060
• Protein Sequence: MASALNSKINPPGTCQGSKADGGAGWRMDCDPQMHVKMCKKIAQLTKVIYALNTRQDEAEASMEALREAHQEELQNAVAETKARLLQEQGCAEEEALLQRIQALESALELQKRLTEEALAESASCRLETKERELRVEAEHAERVLTLSREMLELKADYERRLQHLTSHEATPQGRLPQESPETKSEPGQGPEMQEVLLEVQRLRVENQQLSKDYARKAEELQATYERENEAIRQAMQQSVSQALWQWQEKESDLRKNFQVQESALQAQVRKLEGDLEHRGRKISDLKKYAQKLKERIQDLDVQLKEARQENSELKGTAKKLGEKLAVAKDRMMLQECRGTQQTDAMKTELVSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTDMQTKKEASAETEYMKQQYEEDLRKIKHQTEEEKKHLKDQLVKRLEDLVKKHTVEIKSVRSSVEAERKKLQREVEAQLEEVRKKSEKEIKQLEEEKAALNVKLQNSLLEVLRLEEFIQQNKTRPTGAEESPQELGRQHCSILETQDPCLKLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYREDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQELQEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATEERGGPGQAGSPPGAAGQGSGEGCGLWEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIGRLQTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKVEDVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITTSPSLDPSPSCGRTYKPNQSTDAKTATRTPDGETAQAKEVQQKQGSPHQEWFTKYFSF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Ubiquitination	MHVKMCKKIAQLTKV HHHHHHHHHHHHHHH	38.04	-
46	Phosphorylation	CKKIAQLTKVIYALN HHHHHHHHHHHHHHH	15.93	-
50	Phosphorylation	AQLTKVIYALNTRQD HHHHHHHHHHHCCHH	14.18	-
146	Phosphorylation	EHAERVLTLSREMLE HHHHHHHHHCHHHHH	21.60	24719451
166	Phosphorylation	ERRLQHLTSHEATPQ HHHHHHHHHCCCCCC	26.39	21712546
167	Phosphorylation	RRLQHLTSHEATPQG HHHHHHHHCCCCCCC	26.20	21712546
183	Phosphorylation	LPQESPETKSEPGQG CCCCCCCCCCCCCCC	43.16	21712546
211	Phosphorylation	RVENQQLSKDYARKA HHHCCCCCHHHHHHH	21.10	-
214	Phosphorylation	NQQLSKDYARKAEEL CCCCCHHHHHHHHHH	16.43	-
282	Acetylation	DLEHRGRKISDLKKY CHHHCCCCHHHHHHH	49.76	7670177
287	Acetylation	GRKISDLKKYAQKLK CCCHHHHHHHHHHHH	49.05	7670187
315	Acetylation	RQENSELKGTAKKLG HHHCCCCHHHHHHHH	50.60	7961051
320	Acetylation	ELKGTAKKLGEKLAV CCHHHHHHHHHHHHH	60.30	7961061
352	Phosphorylation	AMKTELVSENKVLRE HHHHHHHHCCCHHCC	48.34	23401153
378	Ubiquitination	QQDQSCLKECPCMKG HCCHHHHHHCCCCCC	62.69	21963094
384	Ubiquitination	LKECPCMKGGTDMQT HHHCCCCCCCCCCCC	61.99	21963094
387	Phosphorylation	CPCMKGGTDMQTKKE CCCCCCCCCCCCHHH	36.65	-
391	Phosphorylation	KGGTDMQTKKEASAE CCCCCCCCHHHHHHH	37.13	-
445	Phosphorylation	KHTVEIKSVRSSVEA HHCEEHHHHHHHHHH	28.55	23403867
448	Phosphorylation	VEIKSVRSSVEAERK EEHHHHHHHHHHHHH	36.26	23403867
558	Phosphorylation	KLAAEEGTSSDEEER HHHHCCCCCCCHHHH	28.47	30177828
559	Phosphorylation	LAAEEGTSSDEEERT HHHCCCCCCCHHHHH	46.80	30177828
560	Phosphorylation	AAEEGTSSDEEERTK HHCCCCCCCHHHHHH	49.21	30177828
582	Phosphorylation	DPQPPLGSLLKEKTS CCCCCHHHHHHHHHH	37.91	24719451
767	Phosphorylation	ALGRQQASSQCPGDS HHHHHHHHHCCCCCC	19.32	28634120
768	Phosphorylation	LGRQQASSQCPGDSK HHHHHHHHCCCCCCC	38.53	28634120
840	Methylation	QKLRDQRRFLEETQQ HHHHHHHHHHHHHHH	34.56	-
902	Phosphorylation	EKPGKGASRPEDLQL CCCCCCCCCHHHHHH	57.97	28348404
948	Phosphorylation	AMSHRNRSFSFNPHP HHCCCCCCCCCCCCC	28.88	23663014
950	Phosphorylation	SHRNRSFSFNPHPGY CCCCCCCCCCCCCCC	25.92	23663014
957	Phosphorylation	SFNPHPGYLTPSMKK CCCCCCCCCCHHHCC	16.32	23663014
959	Phosphorylation	NPHPGYLTPSMKKKK CCCCCCCCHHHCCCC	12.58	23663014
961	Phosphorylation	HPGYLTPSMKKKKVE CCCCCCHHHCCCCCC	37.69	23663014
972	Phosphorylation	KKVEDVPSRVVSVPN CCCCCCCCCCCCCCC	37.24	25690035
976	Phosphorylation	DVPSRVVSVPNLASY CCCCCCCCCCCHHHH	29.06	27251275
1002	Phosphorylation	RINAPPITTSPSLDP HCCCCCCCCCCCCCC	27.31	-
1003	Phosphorylation	INAPPITTSPSLDPS CCCCCCCCCCCCCCC	39.08	-
1010	Phosphorylation	TSPSLDPSPSCGRTY CCCCCCCCCCCCCCC	29.16	-
1016	Phosphorylation	PSPSCGRTYKPNQST CCCCCCCCCCCCCCC	22.60	-
1031	Phosphorylation	DAKTATRTPDGETAQ CCCCCCCCCCCHHHH	22.75	-
1036	Phosphorylation	TRTPDGETAQAKEVQ CCCCCCHHHHHHHHH	29.60	-
1048	Phosphorylation	EVQQKQGSPHQEWFT HHHHHCCCCCHHHHH	19.40	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F184B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F184B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F184B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of F184B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.