F178B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F178B_HUMAN
• UniProt AC: Q8IXR5
• Protein Name: Protein FAM178B
• Gene Name: FAM178B
• Organism: Homo sapiens (Human).
• Sequence Length: 827
• Protein Sequence: MAHEREILKGMYEELKEKSHKPDVELIQHRAWRIDMVSTELESFRKASYIESGPEEFYQRFKKCFSATHIFISIKGKDSQNTAHGYLILNRTLHQQLKIKNPFLAPSSEAVRIPATLPHPGALPFPPYVAKASSDELLNLQKPLQSALGFVILRSSQNWNSKNRQRWSRTKAGQMSHGLQMAGPQETVLALPLREGVQAAATVPILLYNLEDGLSDHPLDQGPRCPARRPCSPASAPAPTSPKKPKIQAPGETFPTDWSPPPVEFLNPRVLQASREAPAQRWVGVVGPQGLRRLAGELPEELEQEHLDLDPKRGLALPEKLFWNTSGLSQQAAAPEFSWGGSGSYFNNLDYLLQEKREQALEQERERLLLQECLNLNSLDLDEEEVPLTPEHRMLVEKYSVSLQTIPPVHPGETVFLPRCHPLPCILDSSLLKPRSHLEGLFLSSPPAQQLSFLRSGLLNILYLHMPDCPVSLLQWLFQLLTWPPETSLGAFGLLWDLIVDGIFLQPDEDKHLWCPSLQEVREAFHSLGAHSPALYPLGPFWHGGRVLPGEAGLNENEEQDAPQEIALDISLGHIYKFLALCAQAQPGAYTDENLMGLIELLCRTSLDVGLRLLPKVDLQQLLLLLLENIREWPGKLQELCCTLSWVSDHHHNLLALVQFFPDMTSRSRRLRSQLSLVVIARMLGQQEMLPLWQEKTQLSSLSRLLGLMRPSSLRQYLDSVPLPPCQEQQPKASAELDHKACYLCHSLLMLAGVVVSCQDITPDQWGELQLLCMQLDRHISTQIRESPQAMHRTMLKDLATQTYIRWQELLTHCQPQAQYFSPWKDI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAHEREILKGM ----CHHHHHHHHHH	42.33	24719451
87	Phosphorylation	QNTAHGYLILNRTLH CCCCCEEEEECCHHH	4.20	27251275
92	Phosphorylation	GYLILNRTLHQQLKI EEEEECCHHHHHHCC	27.76	27251275
93	Phosphorylation	YLILNRTLHQQLKIK EEEECCHHHHHHCCC	2.87	27251275
133	Phosphorylation	PPYVAKASSDELLNL CCHHCCCCHHHHHCC	37.30	28450419
134	Phosphorylation	PYVAKASSDELLNLQ CHHCCCCHHHHHCCH	39.71	28450419
155	Phosphorylation	LGFVILRSSQNWNSK HHHHHHHCCCCCCCC	32.60	28842319
156	Phosphorylation	GFVILRSSQNWNSKN HHHHHHCCCCCCCCC	22.54	28842319
161	Phosphorylation	RSSQNWNSKNRQRWS HCCCCCCCCCCHHHH	23.95	28842319
232	Phosphorylation	CPARRPCSPASAPAP CCCCCCCCCCCCCCC	26.61	29255136
235	Phosphorylation	RRPCSPASAPAPTSP CCCCCCCCCCCCCCC	37.86	29255136
240	Phosphorylation	PASAPAPTSPKKPKI CCCCCCCCCCCCCCC	60.82	29255136
241	Phosphorylation	ASAPAPTSPKKPKIQ CCCCCCCCCCCCCCC	33.39	29255136
253	Phosphorylation	KIQAPGETFPTDWSP CCCCCCCCCCCCCCC	40.61	26657352
430	Phosphorylation	LPCILDSSLLKPRSH CCEECCHHHCCCCHH	37.07	24719451
668	Phosphorylation	FPDMTSRSRRLRSQL CCCCCHHHHHHHHHH	22.86	-
712	Phosphorylation	LLGLMRPSSLRQYLD HHCCCCCHHHHHHHH	31.47	20068231
713	Phosphorylation	LGLMRPSSLRQYLDS HCCCCCHHHHHHHHC	30.19	17081983
797	Ubiquitination	AMHRTMLKDLATQTY HHHHHHHHHHHHHHH	39.61	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F178B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F178B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F178B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of F178B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.