F1712_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F1712_MOUSE
• UniProt AC: A2A699
• Protein Name: Protein FAM171A2
• Gene Name: Fam171a2
• Organism: Mus musculus (Mouse).
• Sequence Length: 822
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MPPPSGPGVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELIPLAAVSVHLLTGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTSGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDNKRDQATSMSQLHLICGGPLEPTSSGDPEAPPPGSLHSAFSSSRDLASSRDDFFRAKPRSASRPAAEPPGARTVEGAGLKSARSVEGPGGLEPSLDEYRRGPAGAAAFLHEPPSPPPSFDHYLGHKGAAESKTPDFLLSQSVDQLARPPSLSQPGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEATPPEGSAAGPARPFPQPDPQRPLMQGHAGAGGDSGGGEGWGGGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGSGGRSTDASLDSGVDVHEARPARRRLPREERERAQLPAPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVVAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
66	N-linked_Glycosylation	ASVDVFGNRTLLAAG EEEEEECCEEEEECC	23.46	-
201	N-linked_Glycosylation	TEASSSGNGSWLELI CCCCCCCCCCHHHHH	43.18	-
221	N-linked_Glycosylation	SVHLLTGNGTEVPLS EEEEECCCCCCCCCC	49.32	-
254	Methylation	GTSIPAWRFDPKSGL CCCCCCEEECCCCCE	28.35	-
265	N-linked_Glycosylation	KSGLWVRNGTGVIRK CCCEEEECCCEEEEE	42.64	-
346	Ubiquitination	YCRRRCLKPRQQHRK HHHHHCCCHHHHHHC	41.60	27667366
353	Ubiquitination	KPRQQHRKLQLSGPS CHHHHHHCCCCCCCC	38.16	22790023
357	Phosphorylation	QHRKLQLSGPSDNKR HHHCCCCCCCCCCHH	35.38	25338131
360	Phosphorylation	KLQLSGPSDNKRDQA CCCCCCCCCCHHHHC	58.29	25338131
368	Phosphorylation	DNKRDQATSMSQLHL CCHHHHCCCHHHEEE	21.23	19060867
369	Phosphorylation	NKRDQATSMSQLHLI CHHHHCCCHHHEEEH	21.32	22817900
371	Phosphorylation	RDQATSMSQLHLICG HHHCCCHHHEEEHHC	29.38	22817900
396	Phosphorylation	PEAPPPGSLHSAFSS CCCCCCCCHHHHHCC	28.78	22817900
403	Phosphorylation	SLHSAFSSSRDLASS CHHHHHCCCHHHHHC	23.96	21082442
409	Phosphorylation	SSSRDLASSRDDFFR CCCHHHHHCCHHHHH	32.95	29233185
410	Phosphorylation	SSRDLASSRDDFFRA CCHHHHHCCHHHHHC	33.84	24899341
421	Phosphorylation	FFRAKPRSASRPAAE HHHCCCCCCCCCCCC	38.84	30372032
423	Phosphorylation	RAKPRSASRPAAEPP HCCCCCCCCCCCCCC	39.79	24899341
442	Phosphorylation	VEGAGLKSARSVEGP CCCCCCCCCCCCCCC	33.68	21454597
445	Phosphorylation	AGLKSARSVEGPGGL CCCCCCCCCCCCCCC	25.00	23527152
455	Phosphorylation	GPGGLEPSLDEYRRG CCCCCCCCHHHHHCC	38.79	-
475	Phosphorylation	AFLHEPPSPPPSFDH HHHCCCCCCCCCCHH	61.83	26239621
479	Phosphorylation	EPPSPPPSFDHYLGH CCCCCCCCCHHHCCC	49.43	26745281
483	Phosphorylation	PPPSFDHYLGHKGAA CCCCCHHHCCCCCCC	19.07	21930439
494	Phosphorylation	KGAAESKTPDFLLSQ CCCCCCCCCCHHHHC	37.05	-
511	Phosphorylation	DQLARPPSLSQPGQL HHHCCCCCCCCCCEE	43.25	26824392
513	Phosphorylation	LARPPSLSQPGQLIF HCCCCCCCCCCEEEE	38.37	26824392
523	Phosphorylation	GQLIFCGSIDHLKDN CEEEEECCHHHHHCC	26.48	26643407
532	Phosphorylation	DHLKDNVYRNVMPTL HHHHCCCHHHHCCCE	11.61	29514104
545	Phosphorylation	TLVIPAHYVRLGGEA CEEEECCEEECCCCC	6.86	29514104
654	Phosphorylation	HPRAWFVSLDGRSNS CCCEEEEEECCCCCC	15.98	22817900
659	Phosphorylation	FVSLDGRSNSQVRHS EEEECCCCCCCCEEE	46.49	25619855
661	Phosphorylation	SLDGRSNSQVRHSYI EECCCCCCCCEEEEE	31.16	25619855
666	Phosphorylation	SNSQVRHSYIDLQAG CCCCCEEEEEEEECC	17.14	25619855
667	Phosphorylation	NSQVRHSYIDLQAGS CCCCEEEEEEEECCC	7.73	25619855
674	Phosphorylation	YIDLQAGSGGRSTDA EEEEECCCCCCCCCC	40.88	25338131
682	Phosphorylation	GGRSTDASLDSGVDV CCCCCCCCCCCCCCH	35.20	29899451
723	Phosphorylation	APPRLALSEDTEPSS CCCCEECCCCCCCCC	28.02	29899451
726	Phosphorylation	RLALSEDTEPSSSES CEECCCCCCCCCCCC	45.82	22817900
729	Phosphorylation	LSEDTEPSSSESRTG CCCCCCCCCCCCCCC	40.02	22817900
730	Phosphorylation	SEDTEPSSSESRTGL CCCCCCCCCCCCCCC	49.17	22817900
731	Phosphorylation	EDTEPSSSESRTGLC CCCCCCCCCCCCCCC	43.88	21183079
733	Phosphorylation	TEPSSSESRTGLCSP CCCCCCCCCCCCCCC	36.77	20415495
735	Phosphorylation	PSSSESRTGLCSPED CCCCCCCCCCCCCCC	43.73	19060867
739	Phosphorylation	ESRTGLCSPEDNSLT CCCCCCCCCCCCCCH	36.04	19060867
744	Phosphorylation	LCSPEDNSLTPLLDE CCCCCCCCCHHHCCC	46.04	21183079
746	Phosphorylation	SPEDNSLTPLLDEVV CCCCCCCHHHCCCEE	16.23	21183079
773	Phosphorylation	RGRSRGDSSRSSASE CCCCCCCCCCCCHHH	30.40	29899451
774	Phosphorylation	GRSRGDSSRSSASEL CCCCCCCCCCCHHHH	40.70	29899451
776	Phosphorylation	SRGDSSRSSASELRR CCCCCCCCCHHHHHH	32.00	29899451
777	Phosphorylation	RGDSSRSSASELRRD CCCCCCCCHHHHHHH	34.40	24899341
779	Phosphorylation	DSSRSSASELRRDSL CCCCCCHHHHHHHCC	38.83	29899451
785	Phosphorylation	ASELRRDSLTSPEDE HHHHHHHCCCCCHHH	31.56	25521595
787	Phosphorylation	ELRRDSLTSPEDELG HHHHHCCCCCHHHHH	46.30	25521595
788	Phosphorylation	LRRDSLTSPEDELGA HHHHCCCCCHHHHHC	31.42	25521595
806	Phosphorylation	DEAGDKKSPWQRREE CCCCCCCCCCCCCCC	36.79	25338131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F1712_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F1712_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F1712_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of F1712_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.