| UniProt ID | F13B_MOUSE | |
|---|---|---|
| UniProt AC | Q07968 | |
| Protein Name | Coagulation factor XIII B chain | |
| Gene Name | F13b | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 669 | |
| Subcellular Localization | Secreted . | |
| Protein Description | The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin.. | |
| Protein Sequence | MMTLRHLPFILLLILSGELYAEEKQCDFPTVENGRIAQYYYTFKSFYFPMSVDKKLSFFCLAGYATESGKQEEQIRCTAEGWSPNPRCYKKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGGKDEEVVHCLSAGWSSQPSCRKEQETCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFGWYPESPICEGRRNRCPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLCENGKWTEPPKCIEEKEKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECVENIENCKPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSPPVCLEPCTIDVDHMNRNNIQLKWKYEGKILHGDLIDFVCKQGYNLSPSIPLSEISAQCNRGDVRYPMCIRKESKGMCASPPVIRNGDIVSSAARTYENGSSVEYRCFDNHFLQGSQNVYCVDGVWTTPPSCLEPCTLSFVEMDKNYLQLKWNFDNRPLILHGEYIEFMCKRDAYISETSIAGSVLRVQCDRGRLKYPKCTPRDRRLSFQEALRTRRQMEKR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 125 | Phosphorylation | GCSSGYKTTGGKDEE CCCCCCCCCCCCCHH | 39.52 | 28576409 | |
| 163 | N-linked_Glycosylation | APELEHGNYSTTQRT CCCCCCCCCCCCCCE | 16.40 | - | |
| 164 | Phosphorylation | PELEHGNYSTTQRTF CCCCCCCCCCCCCEE | 29.04 | 29899451 | |
| 166 | Phosphorylation | LEHGNYSTTQRTFKV CCCCCCCCCCCEEEH | 15.31 | 29899451 | |
| 342 | Phosphorylation | VACEQPPSVENGVAH CCCCCCCCCCCCCCC | 9.03 | 23140645 | |
| 352 | Phosphorylation | NGVAHPHSEIYYSGD CCCCCCCCEEEECCC | 31.79 | 23140645 | |
| 355 | Phosphorylation | AHPHSEIYYSGDKVT CCCCCEEEECCCEEE | 16.31 | 23140645 | |
| 357 | Phosphorylation | PHSEIYYSGDKVTYR CCCEEEECCCEEEEE | 23.72 | 23140645 | |
| 362 | Phosphorylation | YYSGDKVTYRCGGGY EECCCEEEEEECCCE | 13.59 | 23140645 | |
| 363 | Phosphorylation | YSGDKVTYRCGGGYS ECCCEEEEEECCCEE | 11.84 | 23140645 | |
| 546 | N-linked_Glycosylation | SAARTYENGSSVEYR CCCEEEECCCCEEEE | 14.90 | 16944957 | |
| 655 | Phosphorylation | TPRDRRLSFQEALRT CHHHHHHHHHHHHHH | 10.09 | 23140645 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of F13B_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of F13B_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of F13B_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of F13B_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| N-linked Glycosylation | |
| Reference | PubMed |
| "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides."; Bernhard O.K., Kapp E.A., Simpson R.J.; J. Proteome Res. 6:987-995(2007). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-545, AND MASSSPECTROMETRY. | |
| "Proteome-wide characterization of N-glycosylation events by diagonalchromatography."; Ghesquiere B., Van Damme J., Martens L., Vandekerckhove J.,Gevaert K.; J. Proteome Res. 5:2438-2447(2006). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-545, AND MASSSPECTROMETRY. | |
