F120C_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F120C_MOUSE
• UniProt AC: Q8C3F2
• Protein Name: Constitutive coactivator of PPAR-gamma-like protein 2
• Gene Name: Fam120c
• Organism: Mus musculus (Mouse).
• Sequence Length: 1091
• Protein Sequence: MGVQGFQEFLEKRCPGAVVPVDLLKLARTVSRQQQQQHLHRQLPPAALAPGAPRITRGSAPLPPPPLPPAAFGAYSGGAGPSRHHHPAHHFHHHGQAPPGLHPPPPPPLPGARVLVDAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVVMFPGGLGKDRLAEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIRFRVKVFQSLEDHHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTTNQFLMQEVAKQLGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKLSSLPVGPSFLGFRNNRLGNPPLPRNQMGPISPGKPMFSRQVPQKMKYPPPFPMGPNSSLLFSHSVGESHAFSEDAMLQDNSFANWAVSYDSNTSQFPNCLTSKTSPPLGPDSSHSSSSDGDEANGAGSEQITEAVQQQPGWEDPNGDRGAWGQPADAGVSETTVAESEPHIPSLLSMSTRNHMDITIPPLPPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQYVYGVLFSLAETQRKMERLAIRRRLPMEVPSVILKEWSAYKGKSPQTPELVSALTFREWTCPNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGRILHRHELDTFLAQAVSTQLYEPDQLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQPVPWEHCCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLASKVEKMRQSILEGVNMNHPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSFPPPPQARSRGFAGLHPIPPQGGKLEIAGMVVGQWAGSRSSRSRGSFGMQVVSVGGPGKGHGKEQAGRGSKGHKKGNKQGSSDVISKAVELHQSRARSQVNGNNGTLIVEEKSDPLPAPSQCALSRDSNECNNSDDHCLPVKNGEKNHVPEQELEAVAQQKEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	Methylation	PGAPRITRGSAPLPP CCCCCCCCCCCCCCC	34.40	24129315
436	Phosphorylation	RNQMGPISPGKPMFS CCCCCCCCCCCCCCC	30.63	26745281
443	Phosphorylation	SPGKPMFSRQVPQKM CCCCCCCCCCCCCCC	18.62	26643407
887	Phosphorylation	KVEKMRQSILEGVNM HHHHHHHHHHHHCCC	20.83	26060331
900	Phosphorylation	NMNHPPPSALLPSPT CCCCCCCHHCCCCCC	37.00	26060331
905	Phosphorylation	PPSALLPSPTFVPPM CCHHCCCCCCCCCCC	36.22	26060331
907	Phosphorylation	SALLPSPTFVPPMVP HHCCCCCCCCCCCCC	41.42	26060331
915	Phosphorylation	FVPPMVPSLYPVSLY CCCCCCCCCCCCCHH	29.17	26060331
917	Phosphorylation	PPMVPSLYPVSLYSR CCCCCCCCCCCHHHH	13.11	26060331
920	Phosphorylation	VPSLYPVSLYSRAMG CCCCCCCCHHHHHCC	19.65	26060331
922	Phosphorylation	SLYPVSLYSRAMGSF CCCCCCHHHHHCCCC	6.65	26060331
923	Phosphorylation	LYPVSLYSRAMGSFP CCCCCHHHHHCCCCC	20.89	26060331
968	Phosphorylation	GQWAGSRSSRSRGSF EECCCCCCCCCCCCC	31.62	20531401
969	Phosphorylation	QWAGSRSSRSRGSFG ECCCCCCCCCCCCCC	32.91	19854140
971	Phosphorylation	AGSRSSRSRGSFGMQ CCCCCCCCCCCCCCE	42.83	19060867
972	Methylation	GSRSSRSRGSFGMQV CCCCCCCCCCCCCEE	43.60	24129315
974	Phosphorylation	RSSRSRGSFGMQVVS CCCCCCCCCCCEEEE	19.95	29472430
1040	Acetylation	GTLIVEEKSDPLPAP CEEEEEECCCCCCCC	46.80	7627975
1056	Phosphorylation	QCALSRDSNECNNSD HHCCCCCCCCCCCCC	33.16	29899451
1062	Phosphorylation	DSNECNNSDDHCLPV CCCCCCCCCCCEEEC	30.35	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F120C_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F120C_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F120C_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of F120C_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.