F102A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F102A_HUMAN
• UniProt AC: Q5T9C2
• Protein Name: Protein FAM102A
• Gene Name: FAM102A
• Organism: Homo sapiens (Human).
• Sequence Length: 384
• Protein Description: May play a role in estrogen action..
• Protein Sequence: MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCVFRVSVRKELKGGKAYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTPPSTAKSISIPGQDSSLQLTCKGGGTSSGGSSTNSLTGSRPPKARPTILSSGLPEEPDQNLSSPEEVFHSGHSRNSSYASQQSKISGYSTEHSRSSSLSDLTHRRNTSTSSSASGGLGMTVEGPEGSEREHRPPEKPPRPPRPLHLSDRSFRRKKDSVESHPTWVDDTRIDADAIVEKIVQSQDFTDGSNTEDSNLRLFVSRDGSATLSGIQLATRVSSGVYEPVVIESH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
128	Ubiquitination	LLEGYDTKNTRQDNS EEECCCCCCCCCCCC	54.12	-
130	Phosphorylation	EGYDTKNTRQDNSIL ECCCCCCCCCCCCEE	31.12	-
135	Phosphorylation	KNTRQDNSILKVTIG CCCCCCCCEEEEEEE	37.27	24719451
147	Phosphorylation	TIGMFLLSGDPCFKT EEEEHHHCCCCCCCC	43.21	28348404
154	Phosphorylation	SGDPCFKTPPSTAKS CCCCCCCCCCCCCCE	21.85	28348404
169	Phosphorylation	ISIPGQDSSLQLTCK EECCCCCCCEEEEEE	25.67	27251275
170	Phosphorylation	SIPGQDSSLQLTCKG ECCCCCCCEEEEEEC	28.55	27251275
180	Phosphorylation	LTCKGGGTSSGGSST EEEECCCCCCCCCCC	24.01	26330541
181	Phosphorylation	TCKGGGTSSGGSSTN EEECCCCCCCCCCCC	30.20	26330541
182	Phosphorylation	CKGGGTSSGGSSTNS EECCCCCCCCCCCCC	47.19	26657352
185	Phosphorylation	GGTSSGGSSTNSLTG CCCCCCCCCCCCCCC	37.20	26657352
186	Phosphorylation	GTSSGGSSTNSLTGS CCCCCCCCCCCCCCC	34.58	30619164
187	Phosphorylation	TSSGGSSTNSLTGSR CCCCCCCCCCCCCCC	30.44	21955146
189	Phosphorylation	SGGSSTNSLTGSRPP CCCCCCCCCCCCCCC	27.65	23401153
191	Phosphorylation	GSSTNSLTGSRPPKA CCCCCCCCCCCCCCC	32.69	25849741
193	Phosphorylation	STNSLTGSRPPKARP CCCCCCCCCCCCCCC	36.06	21955146
201	Phosphorylation	RPPKARPTILSSGLP CCCCCCCCCHHCCCC	29.06	23312004
204	Phosphorylation	KARPTILSSGLPEEP CCCCCCHHCCCCCCC	20.64	23312004
205	Phosphorylation	ARPTILSSGLPEEPD CCCCCHHCCCCCCCC	40.69	23312004
216	Phosphorylation	EEPDQNLSSPEEVFH CCCCCCCCCHHHHHC	51.93	25849741
217	Phosphorylation	EPDQNLSSPEEVFHS CCCCCCCCHHHHHCC	39.22	29523821
224	Phosphorylation	SPEEVFHSGHSRNSS CHHHHHCCCCCCCCC	27.08	28857561
227	Phosphorylation	EVFHSGHSRNSSYAS HHHCCCCCCCCCCCC	36.36	25849741
230	Phosphorylation	HSGHSRNSSYASQQS CCCCCCCCCCCCCCC	24.50	28348404
231	Phosphorylation	SGHSRNSSYASQQSK CCCCCCCCCCCCCCC	28.41	25849741
240	Phosphorylation	ASQQSKISGYSTEHS CCCCCCCCCCCCCCC	35.10	30174305
242	Phosphorylation	QQSKISGYSTEHSRS CCCCCCCCCCCCCCC	12.96	30174305
243	Phosphorylation	QSKISGYSTEHSRSS CCCCCCCCCCCCCCC	30.74	30174305
244	Phosphorylation	SKISGYSTEHSRSSS CCCCCCCCCCCCCCC	29.27	30174305
247	Phosphorylation	SGYSTEHSRSSSLSD CCCCCCCCCCCCHHH	27.85	25849741
249	Phosphorylation	YSTEHSRSSSLSDLT CCCCCCCCCCHHHCC	27.56	23403867
250	Phosphorylation	STEHSRSSSLSDLTH CCCCCCCCCHHHCCC	33.90	23403867
251	Phosphorylation	TEHSRSSSLSDLTHR CCCCCCCCHHHCCCC	32.89	23401153
253	Phosphorylation	HSRSSSLSDLTHRRN CCCCCCHHHCCCCCC	32.30	23403867
256	Phosphorylation	SSSLSDLTHRRNTST CCCHHHCCCCCCCCC	20.51	23403867
261	Phosphorylation	DLTHRRNTSTSSSAS HCCCCCCCCCCCCCC	31.41	28348404
262	Phosphorylation	LTHRRNTSTSSSASG CCCCCCCCCCCCCCC	29.82	28348404
263	Phosphorylation	THRRNTSTSSSASGG CCCCCCCCCCCCCCC	30.50	28348404
264	Phosphorylation	HRRNTSTSSSASGGL CCCCCCCCCCCCCCC	23.28	28348404
265	Phosphorylation	RRNTSTSSSASGGLG CCCCCCCCCCCCCCC	29.97	28348404
266	Phosphorylation	RNTSTSSSASGGLGM CCCCCCCCCCCCCCC	26.65	28348404
268	Phosphorylation	TSTSSSASGGLGMTV CCCCCCCCCCCCCEE	35.03	29978859
311	Phosphorylation	SFRRKKDSVESHPTW CCCCCCCCCCCCCCC	36.34	29978859
314	Phosphorylation	RKKDSVESHPTWVDD CCCCCCCCCCCCCCC	32.39	26657352
317	Phosphorylation	DSVESHPTWVDDTRI CCCCCCCCCCCCCCC	32.47	27251275
336	Phosphorylation	IVEKIVQSQDFTDGS HHHHHHHCCCCCCCC	22.33	28348404
359	Phosphorylation	LFVSRDGSATLSGIQ EEEECCCCCEEECEE	23.52	28348404
361	Phosphorylation	VSRDGSATLSGIQLA EECCCCCEEECEEEE	24.13	-
369	Phosphorylation	LSGIQLATRVSSGVY EECEEEEEEECCCCC	39.95	-
372	Phosphorylation	IQLATRVSSGVYEPV EEEEEEECCCCCCCE	20.34	21945579
373	Phosphorylation	QLATRVSSGVYEPVV EEEEEECCCCCCCEE	29.44	21945579
376	Phosphorylation	TRVSSGVYEPVVIES EEECCCCCCCEEEEC	20.31	21945579

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F102A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F102A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F102A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of F102A_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.