ETV7_HUMAN - dbPTM
ETV7_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ETV7_HUMAN
UniProt AC Q9Y603
Protein Name Transcription factor ETV7
Gene Name ETV7
Organism Homo sapiens (Human).
Sequence Length 341
Subcellular Localization Nucleus.
Protein Description Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity..
Protein Sequence MQEGELAISPISPVAAMPPLGTHVQARCEAQINLLGEGGICKLPGRLRIQPALWSREDVLHWLRWAEQEYSLPCTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYIKTQRRALVCGPFFGGIFRLKTPTQHSPVPPEEVTGPSQMDTRRGHLLQPPDPGLTSNFGHLDDPGLARWTPGKEESLNLCHCAELGCRTQGVCSFPAMPQAPIDGRIADCRLLWDYVYQLLLDTRYEPYIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKMVQDKHSHLEPLESQEQDRIEFKDKRPEISP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
9PhosphorylationQEGELAISPISPVAA
CCCCEEECCCCCCCC		15.5828348404
12PhosphorylationELAISPISPVAAMPP
CEEECCCCCCCCCCC		19.3928348404
107PhosphorylationPSSGDVLYELLQYIK
CCCHHHHHHHHHHHH		12.3625219547
112PhosphorylationVLYELLQYIKTQRRA
HHHHHHHHHHHHHHH		12.3525219547
115PhosphorylationELLQYIKTQRRALVC
HHHHHHHHHHHHHHC		20.1125219547
133AcetylationFGGIFRLKTPTQHSP
CCCEEEECCCCCCCC		48.487683853
137UbiquitinationFRLKTPTQHSPVPPE
EEECCCCCCCCCCHH		35.9422817900
142UbiquitinationPTQHSPVPPEEVTGP
CCCCCCCCHHHCCCC		33.6921890473
143UbiquitinationTQHSPVPPEEVTGPS
CCCCCCCHHHCCCCC		51.0921890473
207UbiquitinationCRTQGVCSFPAMPQA
CCCCCCCCCCCCCCC		31.6822817900
207PhosphorylationCRTQGVCSFPAMPQA
CCCCCCCCCCCCCCC		31.6821955146
211UbiquitinationGVCSFPAMPQAPIDG
CCCCCCCCCCCCCCC		2.2922817900
212 (in isoform 3)Ubiquitination-29.3221890473
212UbiquitinationVCSFPAMPQAPIDGR
CCCCCCCCCCCCCCC		29.3221890473
213 (in isoform 3)Ubiquitination-46.8421890473
213UbiquitinationCSFPAMPQAPIDGRI
CCCCCCCCCCCCCCC		46.8421890473
216 (in isoform 7)Ubiquitination-11.1321890473
216UbiquitinationPAMPQAPIDGRIADC
CCCCCCCCCCCCCCH		11.1321890473
217UbiquitinationAMPQAPIDGRIADCR
CCCCCCCCCCCCCHH		38.9821890473
217 (in isoform 7)Ubiquitination-38.9821890473
229UbiquitinationDCRLLWDYVYQLLLD
CHHHHHHHHHHHHHC		6.8922817900
233UbiquitinationLWDYVYQLLLDTRYE
HHHHHHHHHHCCCCC		2.5422817900
234UbiquitinationWDYVYQLLLDTRYEP
HHHHHHHHHCCCCCC		2.1021890473
234 (in isoform 2)Ubiquitination-2.1021890473
235UbiquitinationDYVYQLLLDTRYEPY
HHHHHHHHCCCCCCC		9.5721890473
235 (in isoform 2)Ubiquitination-9.5721890473
238UbiquitinationYQLLLDTRYEPYIKW
HHHHHCCCCCCCCCC		33.2221890473
238 (in isoform 6)Ubiquitination-33.2221890473
238 (in isoform 4)Ubiquitination-33.2221890473
238UbiquitinationYQLLLDTRYEPYIKW
HHHHHCCCCCCCCCC		33.2221890473
239UbiquitinationQLLLDTRYEPYIKWE
HHHHCCCCCCCCCCC		24.2921890473
239 (in isoform 4)Ubiquitination-24.2921890473
239UbiquitinationQLLLDTRYEPYIKWE
HHHHCCCCCCCCCCC		24.2921890473
239 (in isoform 6)Ubiquitination-24.2921890473
269UbiquitinationARLWGNHKNRVNMTY
HHHHCCCCCCCCCCH		50.91-
272UbiquitinationWGNHKNRVNMTYEKM
HCCCCCCCCCCHHHH		8.8622817900
277UbiquitinationNRVNMTYEKMSRALR
CCCCCCHHHHHHHHH		32.8721890473
278UbiquitinationRVNMTYEKMSRALRH
CCCCCHHHHHHHHHH		31.5921890473
288UbiquitinationRALRHYYKLNIIKKE
HHHHHHHHHCEEECC		28.0822817900
293UbiquitinationYYKLNIIKKEPGQKL
HHHHCEEECCCCCEE		47.4922817900
293 (in isoform 5)Ubiquitination-47.4921890473
293 (in isoform 1)Ubiquitination-47.4921890473
294UbiquitinationYKLNIIKKEPGQKLL
HHHCEEECCCCCEEE		59.7521890473
294 (in isoform 1)Ubiquitination-59.7521890473
294 (in isoform 5)Ubiquitination-59.7521890473
307PhosphorylationLLFRFLKTPGKMVQD
EEEEHHCCCCCCCCC		39.1529396449
310"N6,N6-dimethyllysine"RFLKTPGKMVQDKHS
EHHCCCCCCCCCCCC		36.78-
310MethylationRFLKTPGKMVQDKHS
EHHCCCCCCCCCCCC		36.7823644510
340PhosphorylationKDKRPEISP------
CCCCCCCCC------		23.9330108239
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ETV7_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ETV7_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ETV7_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AMRP_HUMANLRPAP1physical
21988832
VTNC_HUMANVTNphysical
21988832
ETV6_HUMANETV6physical
26186194
PDLI7_HUMANPDLIM7physical
26186194
ETV6_HUMANETV6physical
28514442
PDLI7_HUMANPDLIM7physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ETV7_HUMAN

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Related Literatures of Post-Translational Modification

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