dbPTM

ERVV1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ERVV1_HUMAN
UniProt AC	B6SEH8
Protein Name	Endogenous retrovirus group V member 1 Env polyprotein
Gene Name	ERVV-1
Organism	Homo sapiens (Human).
Sequence Length	477
Subcellular Localization	Membrane Single-pass type I membrane protein .
Protein Description
Protein Sequence	MTEKFLFLYLSLLPMPLLSQAQWNENSLVSFSKIIASGNHLSNCWICHNFITRSSSYQYILVRNFSLNLTFGSGIPEGQHKSVPLQVSLANSAHQVPCLDLTPPFNQSSKTSFYFYNCSSLNQTCCPCPEGHCDRKNTSEEGFPSPTIHPMSFSPAGCHPNLTHWCPAKQMNDYRDKSPQNRCAAWEGKELITWRVLYLLPKAHTVPTWPKSTVPLGGPLSPACNQTIPAGWKSQLHKWFDSHIPRWACTPPGYVFLCGPQKNKLPFDGSPKITYSTPPVANLYTCINNIQHTGECAVGLLGPRGIGVTIYNTTQPRQKRALGLILAGMGAAIGMIAPWGGFTYHDVTLRNLSRQIDNIAKSTRDSISKLKASIDSLANVVMNNRLALDYLLAEQGGVCAVISKSCCIYVNNSGAIEEDIKKIYDEVTWLHNFGKGDSAGSIWEAVKSALPSLTWFVPLLGPAALNSLLSPLWPLSL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	WNENSLVSFSKIIAS CCCCCCEEHHHHHCC	29.15	24719451
68	N-linked_Glycosylation	LVRNFSLNLTFGSGI EEEEEEEEEEECCCC	35.52	UniProtKB CARBOHYD
178	Phosphorylation	MNDYRDKSPQNRCAA CCCCCCCCCCCCHHH	35.69	-
348	Phosphorylation	GFTYHDVTLRNLSRQ CCCHHHHHHHHHHHH	26.51	24719451
366	Phosphorylation	IAKSTRDSISKLKAS HHHHCHHHHHHHHHH	26.02	28176443
373	Phosphorylation	SISKLKASIDSLANV HHHHHHHHHHHHHHH	25.91	27174698
376	Phosphorylation	KLKASIDSLANVVMN HHHHHHHHHHHHHHC	27.93	27174698
422	Ubiquitination	AIEEDIKKIYDEVTW CCHHHHHHHHHHHHH	47.00	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ERVV1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ERVV1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ERVV1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ERVV1_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ERVV1_HUMAN

Related Literatures of Post-Translational Modification