dbPTM

ERMP1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ERMP1_SCHPO
UniProt AC	O94702
Protein Name	Putative endoplasmic reticulum metallopeptidase 1 {ECO:0000250\|UniProtKB:Q6UPR8}
Gene Name	erm1 {ECO:0000312\|PomBase:SPCC1259.02c}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	822
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MVLVCASSSKCKRNTFLQLAMVLFAVVMARIALYFHNHLDEPLVDPYDANGNPQFSEANALKHVIHLSDDIGYRILGTIEQERAREYIMNEVLALQKQLQDGPNADIHQMEVSLESGDGAHRFDFMNKYVIKKYQNLKNIVVRLSNGTEACKEEAVLINAHVDSTLPSPGATDDALAVAILLEAIRIFISRPVPLTHSIVFLFNDAEESLQDASHMFITQSPLRDTIKCVVNLEACGTTGSEILFQATSNEMIKAYSHVPHPFGTVLADDVFRTGLILSDTDFRQFVQYGNLTGLDMAVVKNSYLYHTKKDLAPYISPGTPQNFGENILAILTYLVSPEADLNNMKSSGTVYFSVFNSLFFMYSKLTSKILNTLVGGLGILLTLRGSEGSFTVALIAQVISIAGIFVIPNIWAYILGNVLDCGMSWFRNEYWPLFIYLPAIFASLFFTESLFKRSEHLALRATIFIFSLLTFIPLPSAYLFTIIDFFMVFALFLNDKILAKPGTVHPLTYFIGSIGAMTVGFESAINLLEIFVPLTGRIGTDKVADNVVATVCVCGFNIYFPLMSPWIQRFRSRCCFRLGLLFSIFVVGFSSFILAKQDTYYDSLHPRRIFVQRMENITSNEVSLHIASADSAPGFDKLSSDLSSLLTDEPVVKTEMDDWNSDWDTVYPFSQFLGSYRIPLNDTVDVTTLPSIKFSNKVVKDNVVNVTVTVEHPGLIWTVVSFDADVLSWSLPEVPSTVRRHHVREVSAYGLDSYSFNMSYLEAPIYFDFVGVDGVGHYPSKASEGRDRASIQLCEKLTNDYLPDWTDTLCIGVVSGNFKLE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
146	N-linked_Glycosylation	NIVVRLSNGTEACKE CEEEECCCCCHHHHH	-
291	N-linked_Glycosylation	RQFVQYGNLTGLDMA HHHHHHCCCCCCCEE	-
617	N-linked_Glycosylation	IFVQRMENITSNEVS HEEEEHHCCCCCCEE	-
682	N-linked_Glycosylation	GSYRIPLNDTVDVTT HCCCCCCCCCCEECC	-
706	N-linked_Glycosylation	VVKDNVVNVTVTVEH EEECCEEEEEEEECC	-
758	N-linked_Glycosylation	GLDSYSFNMSYLEAP CCCCCEECCCCEECC	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ERMP1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ERMP1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ERMP1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ERMP1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ERMP1_SCHPO

Related Literatures of Post-Translational Modification