ERL2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERL2_ARATH
• UniProt AC: Q6XAT2
• Protein Name: LRR receptor-like serine/threonine-protein kinase ERL2
• Gene Name: ERL2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 967
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Description: Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ERL1 and ER..
• Protein Sequence: MRRIETMKGLFFCLGMVVFMLLGSVSPMNNEGKALMAIKASFSNVANMLLDWDDVHNHDFCSWRGVFCDNVSLNVVSLNLSNLNLGGEISSALGDLMNLQSIDLQGNKLGGQIPDEIGNCVSLAYVDFSTNLLFGDIPFSISKLKQLEFLNLKNNQLTGPIPATLTQIPNLKTLDLARNQLTGEIPRLLYWNEVLQYLGLRGNMLTGTLSPDMCQLTGLWYFDVRGNNLTGTIPESIGNCTSFEILDVSYNQITGVIPYNIGFLQVATLSLQGNKLTGRIPEVIGLMQALAVLDLSDNELTGPIPPILGNLSFTGKLYLHGNKLTGQIPPELGNMSRLSYLQLNDNELVGKIPPELGKLEQLFELNLANNNLVGLIPSNISSCAALNQFNVHGNFLSGAVPLEFRNLGSLTYLNLSSNSFKGKIPAELGHIINLDTLDLSGNNFSGSIPLTLGDLEHLLILNLSRNHLNGTLPAEFGNLRSIQIIDVSFNFLAGVIPTELGQLQNINSLILNNNKIHGKIPDQLTNCFSLANLNISFNNLSGIIPPMKNFTRFSPASFFGNPFLCGNWVGSICGPSLPKSQVFTRVAVICMVLGFITLICMIFIAVYKSKQQKPVLKGSSKQPEGSTKLVILHMDMAIHTFDDIMRVTENLDEKYIIGYGASSTVYKCTSKTSRPIAIKRIYNQYPSNFREFETELETIGSIRHRNIVSLHGYALSPFGNLLFYDYMENGSLWDLLHGPGKKVKLDWETRLKIAVGAAQGLAYLHHDCTPRIIHRDIKSSNILLDGNFEARLSDFGIAKSIPATKTYASTYVLGTIGYIDPEYARTSRLNEKSDIYSFGIVLLELLTGKKAVDNEANLHQMILSKADDNTVMEAVDAEVSVTCMDSGHIKKTFQLALLCTKRNPLERPTMQEVSRVLLSLVPSPPPKKLPSPAKVQEGEERRESHSSDTTTPQWFVQFREDISKSSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	N-linked_Glycosylation	WRGVFCDNVSLNVVS CCCEEECCEEEEEEE	26.85	-
79	N-linked_Glycosylation	SLNVVSLNLSNLNLG EEEEEEEECCCCCCC	33.64	-
228	N-linked_Glycosylation	YFDVRGNNLTGTIPE EEEECCCCCEECCCC	41.63	-
239	N-linked_Glycosylation	TIPESIGNCTSFEIL CCCCCCCCCCEEEEE	24.99	-
310	N-linked_Glycosylation	PIPPILGNLSFTGKL CCCCCCCEEEECCEE	29.12	-
334	N-linked_Glycosylation	QIPPELGNMSRLSYL CCCHHHCCCCCEEEE	37.57	-
379	N-linked_Glycosylation	LVGLIPSNISSCAAL CEEEECCCHHHHHHH	32.57	-
414	N-linked_Glycosylation	LGSLTYLNLSSNSFK CCCCEEEECCCCCCC	27.71	-
443	N-linked_Glycosylation	TLDLSGNNFSGSIPL EEECCCCCCCCCCCE	35.67	-
462	N-linked_Glycosylation	LEHLLILNLSRNHLN HHHHHHHCCCCCCCC	29.04	-
469	N-linked_Glycosylation	NLSRNHLNGTLPAEF CCCCCCCCCCCCHHH	33.58	-
534	N-linked_Glycosylation	CFSLANLNISFNNLS CCHHHCCEEEECCCC	27.89	-
539	N-linked_Glycosylation	NLNISFNNLSGIIPP CCEEEECCCCCCCCC	33.31	-
549	N-linked_Glycosylation	GIIPPMKNFTRFSPA CCCCCCCCCCCCCCH	36.95	-
640	Phosphorylation	HMDMAIHTFDDIMRV EEEHHHHCHHHHHHH	23.73	-
648	Phosphorylation	FDDIMRVTENLDEKY HHHHHHHHCCCCCCE	14.59	-
724	Phosphorylation	PFGNLLFYDYMENGS CCCCEEEEEECCCCC	13.21	-
763	Phosphorylation	GAAQGLAYLHHDCTP HHHHHHHHHCCCCCC	16.18	-
818	Phosphorylation	YVLGTIGYIDPEYAR EEECHHCCCCHHHHH	9.78	-
826	Phosphorylation	IDPEYARTSRLNEKS CCHHHHHHCCCCCCC	15.27	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERL2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERL2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERL2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of ERL2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.