ERIC3_HUMAN - dbPTM
ERIC3_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERIC3_HUMAN
UniProt AC Q5RHP9
Protein Name Glutamate-rich protein 3
Gene Name ERICH3
Organism Homo sapiens (Human).
Sequence Length 1530
Subcellular Localization
Protein Description
Protein Sequence MSHSHPAGLLAAYNSLMDKHLAGYFNNTRIRRHLLRSGLITRSGRILSEKEYKLNMMKRDHQKYIRECLAQAIFHKVLDMERYHQLEIKKKLETLARKERIQRFKGEHTRRSVENNMPILSPHPPVGPKSNRGHSVLVDEGHSSPLALTAPRPYTAPGNMQPPIRLQPLPSNPAVETVPKVTSRSRSKTSLLENEALFPIGGKKAVMKFRNSIGNSQRMNSYQLPNINSYMMPIPPPLPPTGKITRENRSETWRRRRFRPTTAPNGLEPLLTKDSRRIHKTSLHSNAAITMIYLGKNVHLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGGKRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPKSRKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKFSAQEIKTGLKEVVTAVEEMTSKGKPGQEVLEDDQENTLKYEYEEDFEVDEEKQGEKSNEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAGLPGLEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSNKESQQLVQKTYTLEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEAPLRAWKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEGGSDPIGQAAAKDAVGLSKDEAPEKQALMLTVLETDKAASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDVEGEEMVTEAEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGEGALAAPEAEPAGKVQAPEGLIPATGQAEELAAKDHDSCAGLEGRAEGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETWHQQDELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGALERKTSGLGQEQEEGSEGQEAATGSGDGRQETGAAEKFRLGLSREGERELSPESLQAMATLPVKPDFTETREKQQHMVQGESETADVSPNNVQV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MSHSHPAGLLA
----CCCCCHHHHHH
24719451
13PhosphorylationPAGLLAAYNSLMDKH
HHHHHHHHHHHHHHH
24719451
48PhosphorylationTRSGRILSEKEYKLN
CCCCEECCHHHHHHH
24719451
52PhosphorylationRILSEKEYKLNMMKR
EECCHHHHHHHHCHH
20049867
185PhosphorylationVPKVTSRSRSKTSLL
CCCCCCCCCCCCCCC
27966365
187PhosphorylationKVTSRSRSKTSLLEN
CCCCCCCCCCCCCCC
27966365
188MethylationVTSRSRSKTSLLENE
CCCCCCCCCCCCCCC
-
189PhosphorylationTSRSRSKTSLLENEA
CCCCCCCCCCCCCCE
27966365
190PhosphorylationSRSRSKTSLLENEAL
CCCCCCCCCCCCCEE
25954137
203MethylationALFPIGGKKAVMKFR
EEECCCCHHHHHHHH
-
212PhosphorylationAVMKFRNSIGNSQRM
HHHHHHHHCCCCCCC
27966365
241PhosphorylationIPPPLPPTGKITREN
CCCCCCCCCCCCCCC
24719451
245PhosphorylationLPPTGKITRENRSET
CCCCCCCCCCCCCHH
24719451
281PhosphorylationDSRRIHKTSLHSNAA
CCCCCCCCCCCCCCE
27174698
282PhosphorylationSRRIHKTSLHSNAAI
CCCCCCCCCCCCCEE
27174698
285PhosphorylationIHKTSLHSNAAITMI
CCCCCCCCCCEEEEE
27174698
290PhosphorylationLHSNAAITMIYLGKN
CCCCCEEEEEECCCC
27174698
293PhosphorylationNAAITMIYLGKNVHL
CCEEEEEECCCCEEE
27174698
408PhosphorylationMGLDKKPSLPKSRKE
CCCCCCCCCCCCHHH
24702127
412PhosphorylationKKPSLPKSRKEKSTE
CCCCCCCCHHHHCCH
24702127
437PhosphorylationKVRKEREYVIPKRNE
CCCCCCEEECCCCHH
-
449UbiquitinationRNEIKENKTSVSAKF
CHHCCCCCCCCHHHH
-
455UbiquitinationNKTSVSAKFSAQEIK
CCCCCHHHHCHHHHH
-
462UbiquitinationKFSAQEIKTGLKEVV
HHCHHHHHHCHHHHH
-
529PhosphorylationQMNGIPQSPLDDKKD
HHCCCCCCCCCCCCC
20873877
566PhosphorylationKDENDGCSESELEED
CCCCCCCCHHHHHHH
24702127
568PhosphorylationENDGCSESELEEDKQ
CCCCCCHHHHHHHHH
24702127
590PhosphorylationTSSRSHPYSSDSEDE
CCCCCCCCCCCCCCC
27732954
591PhosphorylationSSRSHPYSSDSEDES
CCCCCCCCCCCCCCC
27732954
592PhosphorylationSRSHPYSSDSEDESA
CCCCCCCCCCCCCCC
27732954
594PhosphorylationSHPYSSDSEDESAVG
CCCCCCCCCCCCCCC
27732954
618PhosphorylationTDESARRSSSQELSE
CCHHHHHHCHHHHHC
27282143
619PhosphorylationDESARRSSSQELSEN
CHHHHHHCHHHHHCC
27966365
624PhosphorylationRSSSQELSENDKPRK
HHCHHHHHCCCCCCC
29083192
856PhosphorylationRRLGEGGSDPIGQAA
HHCCCCCCCHHHHHH
25404012
871PhosphorylationAKDAVGLSKDEAPEK
HHHHCCCCCCCCHHH
25404012
990PhosphorylationERKEVMRTETRLSPF
HHHHHHHHCCCCCCC
25072903
992PhosphorylationKEVMRTETRLSPFTG
HHHHHHCCCCCCCCC
27080861
995PhosphorylationMRTETRLSPFTGEAE
HHHCCCCCCCCCCHH
25072903
998PhosphorylationETRLSPFTGEAEASR
CCCCCCCCCCHHHHH
25072903
1004PhosphorylationFTGEAEASRMQVSEG
CCCCHHHHHCCCCCC
25072903
1009PhosphorylationEASRMQVSEGSPEEG
HHHHCCCCCCCHHCC
28450419
1012PhosphorylationRMQVSEGSPEEGSLA
HCCCCCCCHHCCCHH
28450419
1017PhosphorylationEGSPEEGSLAKEAFL
CCCHHCCCHHHHEEE
29759185
1073PhosphorylationPKTSLRKTDSEREEV
CCCCCCCCHHHHHHH
-
1075PhosphorylationTSLRKTDSEREEVTR
CCCCCCHHHHHHHHH
-
1081PhosphorylationDSEREEVTRANALKD
HHHHHHHHHHHHHCC
-
1124PhosphorylationAPPNEMGSDAENEAP
CCCCCCCCCCCCCCC
25693802
1166PhosphorylationATPGFEKSLENITAL
CCCCHHHHHHHHHHH
25693802
1171PhosphorylationEKSLENITALRKEGG
HHHHHHHHHHHHCCC
24719451
1183PhosphorylationEGGGERLSEARDTEH
CCCCCCHHCCCCCCC
26091039
1376PhosphorylationKTIANKASSFSDVAE
HHHHHHHHCCHHHHH
28348404
1377PhosphorylationTIANKASSFSDVAEE
HHHHHHHCCHHHHHH
28348404
1379PhosphorylationANKASSFSDVAEEET
HHHHHCCHHHHHHHH
28348404
1386PhosphorylationSDVAEEETWHQQDEL
HHHHHHHHHHHHHHH
28348404
1441PhosphorylationPGALERKTSGLGQEQ
CCHHHHCCCCCCCCC
24702127
1442PhosphorylationGALERKTSGLGQEQE
CHHHHCCCCCCCCCC
27966365
1452PhosphorylationGQEQEEGSEGQEAAT
CCCCCCCCCCCCCCC
24702127
1487PhosphorylationREGERELSPESLQAM
CCCCCCCCHHHHHHH
27966365

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERIC3_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERIC3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERIC3_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ERIC3_HUMAN !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERIC3_HUMAN

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Related Literatures of Post-Translational Modification

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