dbPTM

ERG_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ERG_ARATH
UniProt AC	O82653
Protein Name	GTP-binding protein ERG
Gene Name	ERG
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	437
Subcellular Localization
Protein Description	Has a crucial role in plant growth and development, possibly by influencing mitochondrial division..
Protein Sequence	MKAFRSLRILISISRTTTKTTPRNPHQAQNFLRRFYSAQPNLDEPTSINEDGSSSDSVFDSSQYPIDDSNVDSVKKPKEATWDKGYRERVNKAFFGNLTEKGKVKVAEEESSEDDEDSVDRSRILAKALLEAALESPDEELGEGEVREEDQKSLNVGIIGPPNAGKSSLTNFMVGTKVAAASRKTNTTTHEVLGVLTKGDTQVCFFDTPGLMLKKSGYGYKDIKARVQNAWTSVDLFDVLIVMFDVHRHLMSPDSRVVRLIKYMGEEENPKQKRVLCMNKVDLVEKKKDLLKVAEEFQDLPAYERYFMISGLKGSGVKDLSQYLMDQAVKKPWEEDAFTMSEEVLKNISLEVVRERLLDHVHQEIPYGLEHRLVDWKELRDGSLRIEQHLITPKLSQRKILVGKGGCKIGRIGIEANEELRRIMNRKVHLILQVKLK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
111	Phosphorylation	VKVAEEESSEDDEDS EEEECCCCCCCCCCC	42.16	19880383
112	Phosphorylation	KVAEEESSEDDEDSV EEECCCCCCCCCCCC	48.61	19880383
136	Phosphorylation	LLEAALESPDEELGE HHHHHHHCCCHHCCC	38.20	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ERG_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ERG_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ERG_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ERG_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ERG_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Site-specific phosphorylation profiling of Arabidopsis proteins bymass spectrometry and peptide chip analysis."; de la Fuente van Bentem S., Anrather D., Dohnal I., Roitinger E.,Csaszar E., Joore J., Buijnink J., Carreri A., Forzani C.,Lorkovic Z.J., Barta A., Lecourieux D., Verhounig A., Jonak C.,Hirt H.; J. Proteome Res. 7:2458-2470(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111 AND SER-112, ANDMASS SPECTROMETRY.	18433157 [Abstract]