dbPTM

EPT1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	EPT1_SCHPO
UniProt AC	O13747
Protein Name	RING finger protein ETP1 homolog
Gene Name	SPAC16E8.13
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	547
Subcellular Localization	Cytoplasm .
Protein Description	May act as a cytoplasmic retention protein with a role in regulating nuclear transport..
Protein Sequence	MYYYLEIECESPVKDIFTCNKRRASKVVGNSFGGDHFNFRLGEIKLLSMDFPSSKVPEVEETSLGHGVVHLYRVFPSESHEFDAPGLILAILAIPLYMSPSDVLGFLGEKHCKSIQHIRLLKTKDPNRIMALLKFKDQASVIRFYTEFNGKAFSQIDPETCHVLHIDKVNIKYPMESSDSSSTEQQLVGPSSKPFASTTPALIELPTCVVCLERMDSSITGLITIVCQHTFHCPCLQKWGNSSCPVCRYTQKVQSSEFQSKCTVCCYDKDLWICLICGNIGCGRYHDAHAKQHYVDTAHCYAMELETQRVWDYAGDNYVHRLLQSETDGKLVELSTDGKSSGWTGSSATESKLRDKMGLEYTQILVSQLESQRLYYESHLSNMSQKLSRVNEELVLKTKIATASSNANTDLRSRVDISESKLKKRDDKLKRVSSQLEHLKHNYEEEKSMNENLLVRIQTLEKQNTTKSDQIVSMQFQINDLNEQLRDLMFTISASQEIQKMGQSEELQNGTIVLPNNSTVRSNSVKSKKKKKKKPVVPSSSGSLGTD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
433	Phosphorylation	DDKLKRVSSQLEHLK HHHHHHHHHHHHHHH	19.19	21712547
434	Phosphorylation	DKLKRVSSQLEHLKH HHHHHHHHHHHHHHH	35.61	28889911
518	Phosphorylation	TIVLPNNSTVRSNSV EEECCCCCCCCCCCC	34.61	27738172
522	Phosphorylation	PNNSTVRSNSVKSKK CCCCCCCCCCCCCCC	29.17	21712547
524	Phosphorylation	NSTVRSNSVKSKKKK CCCCCCCCCCCCCCC	31.97	24763107
543	Phosphorylation	VVPSSSGSLGTD--- CCCCCCCCCCCC---	26.10	21712547
546	Phosphorylation	SSSGSLGTD------ CCCCCCCCC------	43.77	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of EPT1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of EPT1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of EPT1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of EPT1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of EPT1_SCHPO

Related Literatures of Post-Translational Modification