EPMIP_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EPMIP_MOUSE
• UniProt AC: Q8VEH5
• Protein Name: EPM2A-interacting protein 1
• Gene Name: Epm2aip1
• Organism: Mus musculus (Mouse).
• Sequence Length: 606
• Subcellular Localization: Endoplasmic reticulum.
• Protein Sequence: MWMTPKRIRMEVDEALVFRPEWTQRYLVVEPAEGDGALCLVCRRLVASTRERDVRRHYEAEHEFYERFVGDEERAALVERLRQGDMSLAAVLTPEERATRAGLGLCRFLALKGRGWGEGDFVHQCMEVLLREVLPDHVGVLEGIDLSPEITRQRILSIDSNLRSQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGRDLEVQEDLLTIINLTHHFSVGALMSAILEALQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLELLSSYDVDINQIINTISEWVVMIKTRGVRRPEFQPLLTESESEHGERVNGRCLNNWLRRGKTLKLIFSLRKEIEAFLVSVGATTVHFSDKQWLCDFGFLVDIMDYLREISEELQISKVFAAAAFERICTFEGKLSSLQRHMEEVNLTDFPAFSIIVDELKQQFKEDQKIFDPDRYQMVISRLQKDFERHFKDLRFIKKDLELFSNPFSFKPEYAPISVRVELTKLQANTDLWNEYRVKDLGQFYAGLSGEAYPIIKGVAYKVASLFDSNQICDKAFAYLTRNQHTLSQPLTDEHLQALFRVATTEMDPRWDDLVRERNDS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MWMTPKRIRME ----CCCCCCHHEEE	15.33	-
112	Ubiquitination	LCRFLALKGRGWGEG HHHHHHHCCCCCCCC	40.74	22790023
147	Phosphorylation	VLEGIDLSPEITRQR CCCCCCCCHHHHHHH	19.42	22817900
151	Phosphorylation	IDLSPEITRQRILSI CCCCHHHHHHHHHHC	21.06	23984901
157	Phosphorylation	ITRQRILSIDSNLRS HHHHHHHHCCHHHHH	23.21	27180971
324	Phosphorylation	PEFQPLLTESESEHG CCCCCCCCCCHHHCC	45.18	26525534
326	Phosphorylation	FQPLLTESESEHGER CCCCCCCCHHHCCCC	40.98	26525534
421	Phosphorylation	CTFEGKLSSLQRHME HCCHHHHHHHHHHHH	32.27	22345495
422	Phosphorylation	TFEGKLSSLQRHMEE CCHHHHHHHHHHHHH	38.67	22802335
496	Ubiquitination	FSNPFSFKPEYAPIS HCCCCCCCCCCCCEE	35.42	22790023
560	Ubiquitination	DSNQICDKAFAYLTR CHHHHHHHHHHHHHC	40.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EPMIP_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EPMIP_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EPMIP_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of EPMIP_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.