EPIPL_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EPIPL_MOUSE
• UniProt AC: Q8R0W0
• Protein Name: Epiplakin {ECO:0000303|PubMed:12791695}
• Gene Name: Eppk1 {ECO:0000312|MGI:MGI:2386306}
• Organism: Mus musculus (Mouse).
• Sequence Length: 6548
• Subcellular Localization: Cytoplasm, cytoskeleton . Apicolateral cell membrane . Basolateral cell membrane . Cell junction . Cell junction, hemidesmosome . Cell junction, tight junction . Cell projection . Apicolateral cell membrane localization is keratin filaments-dependent
• Protein Description: Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress. [PubMed: 16382146]
• Protein Sequence: MNGQAPPHDVVVANGTEKFIVPKIKKNQLGASTPSRPQAEAALPTTARSIAGVYVEASGQTQSIYAAIKQGLLPTGLGLTLLEAQAATGGLVDLAQGQLLPVSEALRRGLVGLELKEKLLAAERAVTGYPDPYGGEKLSLFQAIKKEVVDRTLGWRLLEAQLATGGLVDPTQGVQVAPELACQQGLLDKETWLSLVESEPSMGTPGFSDPNTLEQLPYSVLLGRCVQDPSSGLPLLPLKTTFHTLAGAASASMLLEAGVLNEEMVRDLQEGMLVVSDVGTRPEVRRYLEGTGGLAGVVLLPGGHKKSFFQATVEHLVSKGIALQLLEAQAATRTLVHPTTGQRLWVEEAVKAGLVGPELHEQLLVAEQAVTGYYDPFSSSRIPVFQAMKKGLVDQPLALRLLDAQLATGGLICPARRFRLPLEAALRFGCLDEETRQRLSQAMGFSDPTTHDRLGYEQLLALSVTDPETGLAFLPLPGMSHANEPQGPTFIDHCTRQALSKATTSISVGRYQGRPVSLWELLFSESVPVKKRAMLAQRHQEGALSVEELAAELKNIVEQAAATAKVTFAGLRDTVTPGELLKAEIINQDLFEQLERGQTSAQDVGSLDSVQRYLQGTGSIAGLLLPDSQERLSIYEARSKGLLRPGTALILLEAQAATGFIIDPKENKRYSVEEALRAGVIGPDVYAKLLSAEHAVTGYTDPYSGEQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDQILNSILLDPSDDTKGFFDPNTHENLTYLQLLERCVHDSETGLHLLPLSSTRPQLVDSSTRQAFQKLLLSVKYGRFRGQRVSAWELVNSEYFTEDRRRQLLQRYRQRKITLEQVTQLLEKEMRRWTDITLPALQGQVTAYQLLEAHIINQELLDQVLTGTISPDALLQVGDVHRYLRGSGTVGGVLLKPSNQRISLYQAMKQKLLPPSTALALLEAQAATGTITDPCSMETLSVDEAVCRGVVGAEVYGKLKRAEHSITGYRDPFSGKKVSLFRAMKKGLVPVEQATRLLEAQVSTGGVVDPTTHLHLPMPVAVQRGCIDREMEAALSRSPETFPTPDGRGHTSYAQLLEHCLQDKASGLHLLPLTEDAPNVPTDTQIQETLQASAGTEDGLSLWDLLTSCHFTEEQRRGYLEDVKVGKISVPQLQNTVRSWVHSAKLLARARITVPGPRGEVPATWLRDAGIITQETLEALAQGMQSPDEVAKQPTVKVCLWGTGCVAGVLLQPSGTKLSIAQAVRDGLLPTGLGQQLLEAQVASGFLVNPLTNQRLSVEGAVKAGLVGMEQSEHLRQVEKAVTGYSDPFSGGSLSLWQAMEKGLVTQSEAFPLLQVQLATGGVVDPVHGVHLPQEVAYKLGLLDEQTSRVLTATGKENKLFFDPNSREKVTYQQLRELCVLDADTGLWLLPLPQGTVLEVDDHTAVALRAMKVPINMGRFQGHSVSLWDLLHSEYVGAEKRRELVALCCSGRAAALRQVIGMLTTLVEAAEKQPSQATFKGLRKQVSAGDLFRSQLITKQTLDELNQGKRTVQEVTEMDSVRRSLEGGNFIAGVLIQDTKEKMSIPEALRRHILRPGTALVLLEAQAATGFIIDPVENRKLTVEQAFQAGMFGKETYMKLLSAERAVTGYTDPYTGEQISLFQAMQRDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFNEEMNRILSDPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYMLEIVKKGETYTYIDEATRQALTSRTVKMYVGKFAGQTVSVWDLLSSQYFTEGRRRKLLREYRAQNIGLENLLEVITSTVEETEKQSQIFKVPGIHGDVTAAELFNSGILNKKTLDALRSGDRGFQDLRWLEDVRVYLEGSNYIAGVIAPLTQKVMSFYEASREELIPAGFAAQMLEAQAATGYLMDPCTNQRLCVDEAIAAGLVGEDLRERLVNAEMAAKGYKDPATGETIPLYQAMERKLVGREEALRLLEVQVATGGVIDPRHHHRVPLDTACQRGCMCDDSLVLIADQKHMRKRFVDPNTQEKVTYQELQDRCQREEKSGWALFPVVKDKKDIEYVDEATKRALEAEQVEVTVGRYRGQRRSVWELLNSEYVSEEKKMELVRLYKEDTTRALQKVVELILQMIADKERRSRQLWFRGLRTQVTAEELLRSEVITKQTLEDLEEGRTTVDQIERKEDVKRYLKGTSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRCYQAGGLTVHDVTTTLTSLLARAKDGSPRGDPQGALGKATMEVKRGHLRGHEVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPREDPQGALGKATMEVKRGHLRGHVVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVKNHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDQEMNSILADPGDDTKGFFDPNTHENLTYLQLLQRATIDPETGLLFLSLSKG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Malonylation	FIVPKIKKNQLGAST EECCCCHHCCCCCCC	54.09	26320211
32	Phosphorylation	KKNQLGASTPSRPQA HHCCCCCCCCCCHHH	38.77	29472430
33	Phosphorylation	KNQLGASTPSRPQAE HCCCCCCCCCCHHHH	25.42	28507225
35	Phosphorylation	QLGASTPSRPQAEAA CCCCCCCCCHHHHHH	57.59	29472430
413	S-palmitoylation	LATGGLICPARRFRL HHCCCEECCHHHCCC	2.31	28526873
576	Phosphorylation	AGLRDTVTPGELLKA CCCCCCCCHHHHHHH	27.89	-
946	Ubiquitination	TVGGVLLKPSNQRIS CCCCEEECCCCCCCC	42.09	27667366
1029	Phosphorylation	PFSGKKVSLFRAMKK CCCCCCHHHHHHHHC	30.58	-
1086	Phosphorylation	REMEAALSRSPETFP HHHHHHHCCCCCCCC	26.45	29472430
1088	Phosphorylation	MEAALSRSPETFPTP HHHHHCCCCCCCCCC	24.58	29472430
1091	Phosphorylation	ALSRSPETFPTPDGR HHCCCCCCCCCCCCC	38.00	29472430
1537	Phosphorylation	KGLRKQVSAGDLFRS HHHHHHCCHHHHHHH	24.84	27087446
1551	Phosphorylation	SQLITKQTLDELNQG HHHCCHHHHHHHHCC	37.42	-
1652	Phosphorylation	ETYMKLLSAERAVTG HHHHHHHHHHHHHCC	38.22	27149854
1727	Phosphorylation	EEMNRILSDPSDDTK HHHHHHHCCCCCCCC	45.14	20531401
2123	Phosphorylation	VEVTVGRYRGQRRSV EEEEEECCCCCCHHH	17.11	24719451
2136	Phosphorylation	SVWELLNSEYVSEEK HHHHHHCCCCCCHHH	30.21	24719451
2161	Ubiquitination	DTTRALQKVVELILQ HHHHHHHHHHHHHHH	49.45	-
2173	Ubiquitination	ILQMIADKERRSRQL HHHHHHCHHHHHHHH	44.06	-
2187	Phosphorylation	LWFRGLRTQVTAEEL HHHHHHHHHCCHHHH	32.22	29472430
2190	Phosphorylation	RGLRTQVTAEELLRS HHHHHHCCHHHHHCC	20.66	29472430
2290	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
2310	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
2430	Phosphorylation	LQLAGKGSSVHHLSE EEECCCCCCHHHHCH	32.45	-
2508	Phosphorylation	LARAKDGSPRGDPQG HHHCCCCCCCCCCCC	22.89	26239621
2521	Phosphorylation	QGALGKATMEVKRGH CCHHHHHEEEEECCC	19.83	28059163
2525	Malonylation	GKATMEVKRGHLRGH HHHEEEEECCCCCCC	39.08	26320211
2558	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
2559	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
2561	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
2563	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
2572	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
2573	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
2594	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
2603	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
2605	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
2606	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
2615	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
2652	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
2653	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
2656	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
2694	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
2696	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
2705	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
2707	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
2711	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
2712	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
2719	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
2720	Oxidation	GILDRDTMRELAQGT CCCCHHHHHHHHHCC	3.52	17242355
2748	S-palmitoylation	RYLGGSSCIAGVLVP HHHCCCCCEEEEEEE	2.37	28526873
2805	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
2825	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
3040	Malonylation	GKATMEVKRGHLRGH CHHEEEEECCCCCCC	39.08	26320211
3073	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
3074	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
3076	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
3078	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
3087	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
3088	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
3109	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
3118	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
3120	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
3121	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
3130	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
3167	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
3168	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
3171	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
3209	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
3211	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
3220	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
3222	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
3226	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
3227	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
3234	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
3320	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
3340	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
3460	Phosphorylation	LQLAGKGSSVHHLSE EEECCCCCCHHHHCH	32.45	-
3538	Phosphorylation	LARAKDGSPRXDPQG HHHCCCCCCCCCCCC	27.86	-
3555	Malonylation	GKATMEVKRGHLRGH CHHEEEEECCCCCCC	39.08	26320211
3588	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
3589	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
3591	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
3593	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
3602	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
3603	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
3624	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
3633	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
3635	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
3636	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
3645	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
3682	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
3683	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
3686	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
3724	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
3726	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
3735	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
3737	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
3741	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
3742	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
3749	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
3835	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
3855	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
3975	Phosphorylation	LQLAGKGSSVHHLSE EEECCCCCCHHHHCH	32.45	-
4053	Phosphorylation	LARAKDGSPRXDPQG HHHCCCCCCCCCCCC	27.86	-
4070	Malonylation	GKATMEVKRGHLRGH CHHEEEEECCCCCCC	39.08	26320211
4103	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
4104	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
4106	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
4108	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
4117	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
4118	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
4139	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
4148	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
4150	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
4151	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
4160	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
4197	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
4198	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
4201	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
4239	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
4241	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
4250	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
4252	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
4256	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
4257	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
4264	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
4350	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
4370	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
4585	Malonylation	GKATMEVKRGHLRGH CHHEEEEECCCCCCC	39.08	26320211
4618	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
4619	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
4621	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
4623	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
4632	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
4633	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
4654	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
4663	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
4665	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
4666	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
4675	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
4712	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
4713	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
4716	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
4754	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
4756	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
4765	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
4767	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
4771	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
4772	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
4779	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
4865	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
4885	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
5005	Phosphorylation	LQLAGKGSSVHHLSE EEECCCCCCHHHHCH	32.45	-
5083	Phosphorylation	LARAKDGSPRXDPQG HHHCCCCCCCCCCCC	27.86	-
5100	Malonylation	GKATMEVKRGHLRGH CHHEEEEECCCCCCC	39.08	26320211
5133	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
5134	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
5136	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
5138	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
5147	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
5148	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
5169	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
5178	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
5180	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
5181	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
5190	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
5227	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
5228	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
5231	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
5269	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
5271	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
5280	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
5282	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
5286	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
5287	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
5294	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
5380	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
5400	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
5615	Malonylation	GKATMEVKRGHLRGH CHHEEEEECCCCCCC	39.08	26320211
5648	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
5649	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
5651	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
5653	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
5662	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
5663	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
5684	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
5693	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
5695	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
5696	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
5705	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
5742	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
5743	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
5746	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
5784	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
5786	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
5795	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
5797	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
5801	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
5802	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
5809	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
5895	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
5915	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854
6035	Phosphorylation	LQLAGKGSSVHHLSE EEECCCCCCHHHHCH	32.45	-
6113	Phosphorylation	LARAKDGSPREDPQG HHHCCCCCCCCCCCC	30.80	22324799
6130	Malonylation	GKATMEVKRGHLRGH CHHHHHHHCCCCCCC	39.08	26320211
6163	Phosphorylation	KELLAQFSSGSLTLP HHHHHHHHCCCCCHH	23.01	23140645
6164	Phosphorylation	ELLAQFSSGSLTLPM HHHHHHHCCCCCHHH	33.42	23140645
6166	Phosphorylation	LAQFSSGSLTLPMLK HHHHHCCCCCHHHHH	21.82	23140645
6168	Phosphorylation	QFSSGSLTLPMLKRR HHHCCCCCHHHHHHH	30.43	23140645
6177	Phosphorylation	PMLKRRLTTIIEEAE HHHHHHHHHHHHHHH	17.71	-
6178	Phosphorylation	MLKRRLTTIIEEAEE HHHHHHHHHHHHHHH	25.25	29899451
6199	Malonylation	KPRDASLKQQDTGAR CCCCCCCCCCCCCCC	43.34	26320211
6208	Phosphorylation	QDTGARGSGTSPDEG CCCCCCCCCCCCCCC	33.09	17203969
6210	Phosphorylation	TGARGSGTSPDEGDA CCCCCCCCCCCCCCC	38.49	17203969
6211	Phosphorylation	GARGSGTSPDEGDAQ CCCCCCCCCCCCCCC	33.60	25521595
6220	Phosphorylation	DEGDAQDSSESARQQ CCCCCCCCHHHHHHH	24.75	20469934
6257	Phosphorylation	SVWKVLFSSYLSETR HHHHHHHHHHCCHHH	17.57	29472430
6258	Phosphorylation	VWKVLFSSYLSETRR HHHHHHHHHCCHHHH	23.82	29472430
6261	Phosphorylation	VLFSSYLSETRREEL HHHHHHCCHHHHHHH	28.79	29472430
6299	Malonylation	ETEERLSKVSFPGLR HHHHHHHCCCCHHHH	46.63	26320211
6301	Phosphorylation	EERLSKVSFPGLRRQ HHHHHCCCCHHHHHC	29.47	27149854
6310	Phosphorylation	PGLRRQVSASELCTS HHHHHCCCHHHHHHC	20.10	25521595
6312	Phosphorylation	LRRQVSASELCTSGI HHHCCCHHHHHHCCC	24.48	22324799
6316	Phosphorylation	VSASELCTSGILDRD CCHHHHHHCCCCCHH	42.48	23984901
6317	Phosphorylation	SASELCTSGILDRDT CHHHHHHCCCCCHHH	23.88	26643407
6324	Phosphorylation	SGILDRDTMRELAQG CCCCCHHHHHHHHHC	21.01	26643407
6410	Phosphorylation	PVNNRRLSVEEAVAA CCCCCCCCHHHHHHH	26.18	26239621
6430	Phosphorylation	EIQEKLLSAERAVTG HHHHHHHCCHHHHCC	38.22	27149854

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EPIPL_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EPIPL_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EPIPL_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of EPIPL_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-6310, AND MASSSPECTROMETRY.
PubMed: 19367708

"Specific phosphopeptide enrichment with immobilized titanium ionaffinity chromatography adsorbent for phosphoproteome analysis.";
Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.;
J. Proteome Res. 7:3957-3967(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-6310, AND MASSSPECTROMETRY.
PubMed: 18630941

"Large-scale phosphorylation analysis of mouse liver.";
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-6310, AND MASSSPECTROMETRY.
PubMed: 17242355