dbPTM

ENT6_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ENT6_ARATH
UniProt AC	Q944N8
Protein Name	Equilibrative nucleotide transporter 6
Gene Name	ENT6
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	418
Subcellular Localization	Cell membrane Multi-pass membrane protein . Plasma membrane.
Protein Description	Nucleoside tranpsorter that can mediate uptake of adenosine, uridine, guanosine or cytidine when expressed in a heterologous system (yeast)..
Protein Sequence	MADIYEHQVPEKLRGKYQAMIVYCILGFGSLISWNSMLTTADYYYKVFPDYHPSRVLTLVYQPFAFGAIVILAYHESKTSTRKRNLIGYILYTISTFLLIVLDLATKGRGGFGPYTGLCAVVAAFGLADATVQGGMFGDLSLMCPELVQSYMGGMAVAGALTSALRLITKAAFEKSNNGLRKGAMMFLAISTCIELLSVMLYAYVLPKLPIVMYYRRKAASQGSKTVSADLAAAGIQNQSDLSDDDSKNQRLSKKELLFQNIDHAVNLFLIYVCTLSIFPGFLYENTGQHGLGAWYALVLVAMYNCWDLVGRYTPLVKWLNIENRKLITIAVLSRYLLIPAFYFTAKYGDQGWMIMLVSVLGLTNGHLTVCIMTIAPKGYKGPEQNALGNLLVIFLLGGIFAGVALDWLWLIGKKNAF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
228	Phosphorylation	SQGSKTVSADLAAAG HCCCCCHHHHHHHHC	15308754
240	Phosphorylation	AAGIQNQSDLSDDDS HHCCCCHHHCCCCCH	15308754
243	Phosphorylation	IQNQSDLSDDDSKNQ CCCHHHCCCCCHHHH	15308754

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ENT6_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ENT6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ENT6_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
GAT2_ARATH	AT5G41800	physical	24833385

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ENT6_ARATH

Related Literatures of Post-Translational Modification