EMIL3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EMIL3_HUMAN
• UniProt AC: Q9NT22
• Protein Name: EMILIN-3
• Gene Name: EMILIN3
• Organism: Homo sapiens (Human).
• Sequence Length: 766
• Subcellular Localization: Secreted, extracellular space, extracellular matrix.
• Protein Sequence: MGRRRLLVWLCAVAALLSGAQARGTPLLARPAPPGASRYSLYTTGWRPRLRPGPHKALCAYVVHRNVTCILQEGAESYVKAEYRQCRWGPKCPGTVTYRTVLRPKYKVGYKTVTDLAWRCCPGFTGKRCPEHLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSPHGRKGPGLFGERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVGPGDRARGPLTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVRPGQAN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	PPGASRYSLYTTGWR CCCCCCEEEEECCCC	17.50	-
66	N-linked_Glycosylation	CAYVVHRNVTCILQE HHHHHHCCEEEEECC	20.69	UniProtKB CARBOHYD
100	Phosphorylation	PGTVTYRTVLRPKYK CCCEEEEEECCCCCC	17.30	23898821
106	Phosphorylation	RTVLRPKYKVGYKTV EEECCCCCCCCCEEH	17.37	23898821
206	Phosphorylation	TLSGLVASHEDPNRM HHHHHHHCCCCCCCC	21.67	26657352
214	Phosphorylation	HEDPNRMTGGPRAPA CCCCCCCCCCCCCCC	35.43	-
256	Phosphorylation	DEILSKVTEVSNTLQ HHHHHHHHHHHHHHH	34.11	28176443
259	Phosphorylation	LSKVTEVSNTLQTKV HHHHHHHHHHHHHHH	20.19	28176443
261	Phosphorylation	KVTEVSNTLQTKVQL HHHHHHHHHHHHHHH	16.85	28176443
314	Phosphorylation	RLHRLWGSLLDGFEQ HHHHHHHHHHHHHHH	17.74	22817900
328	Phosphorylation	QKLQGVQSECDLRVQ HHHHHHHHHHHHHHH	37.47	29083192
421	Phosphorylation	APAGDELTRLSAAML CCCHHHHHHHHHHHH	27.76	23612710
443	N-linked_Glycosylation	LEGLETLNGTEGGAR HHHHHHHCCCCCCCC	63.86	UniProtKB CARBOHYD
492	Phosphorylation	AGELSHDSASPGRSA HHHHCCCCCCCCCCC	25.81	-
522	O-linked_Glycosylation	VSLETSCTPSTTSAI HHHCCCCCHHHHHHH	21.75	OGP
562	N-linked_Glycosylation	AALLQQLNGTVAEVQ HHHHHHHCCHHHHHH	39.49	UniProtKB CARBOHYD
616	N-linked_Glycosylation	SDAFLAANTSLDERE HHHHHHHCCCCHHHH	25.29	UniProtKB CARBOHYD
715	Phosphorylation	AGLDSLPTEPLRPRE CCCCCCCCCCCCCCC	56.37	24719451
732	N-linked_Glycosylation	WSHVDQLNRTLAQHT HHHHHHHHHHHHHHH	29.29	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EMIL3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EMIL3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EMIL3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of EMIL3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.