| UniProt ID | EMC2_MOUSE | |
|---|---|---|
| UniProt AC | Q9CRD2 | |
| Protein Name | ER membrane protein complex subunit 2 | |
| Gene Name | Emc2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 297 | |
| Subcellular Localization | Nucleus . Cytoplasm. | |
| Protein Description | ||
| Protein Sequence | MAKVTERYDVTWEEMRDKMRKWREENSRNSEQIMEVGEELINDYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKTVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKMKKDNIKYASWAANQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAKVTERYD ------CCCCCCCCC | 18.28 | - | |
| 18 | Ubiquitination | TWEEMRDKMRKWREE CHHHHHHHHHHHHHH | 30.18 | - | |
| 119 | Phosphorylation | RILQEDPTNTAARKR HHHHHCCCCHHHHHH | 58.48 | 28066266 | |
| 121 | Phosphorylation | LQEDPTNTAARKRKI HHHCCCCHHHHHHHH | 24.95 | 26824392 | |
| 220 | Acetylation | KYFAQALKLNNRNMR HHHHHHHHCCCHHHH | 52.78 | 23954790 | |
| 255 | Acetylation | KMKKDNIKYASWAAN HCCCCCHHHHHHHHH | 40.81 | 23954790 | |
| 256 | Phosphorylation | MKKDNIKYASWAANQ CCCCCHHHHHHHHHH | 11.32 | 21082442 | |
| 258 | Phosphorylation | KDNIKYASWAANQIN CCCHHHHHHHHHHHH | 17.73 | 22817900 | |
| 281 | Phosphorylation | SKKETKYSLKAVEDM CCCCCHHHHHHHHHH | 25.58 | 24719451 | |
| 291 | Phosphorylation | AVEDMLETLQITQS- HHHHHHHHHHHHCC- | 21.72 | 21454597 | |
| 295 | Phosphorylation | MLETLQITQS----- HHHHHHHHCC----- | 15.14 | 21454597 | |
| 297 | Phosphorylation | ETLQITQS------- HHHHHHCC------- | 33.27 | 29899451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of EMC2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of EMC2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of EMC2_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of EMC2_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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