ELMD1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ELMD1_MOUSE
• UniProt AC: Q3V1U8
• Protein Name: ELMO domain-containing protein 1
• Gene Name: Elmod1
• Organism: Mus musculus (Mouse).
• Sequence Length: 326
• Protein Description: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family..
• Protein Sequence: MKHFLRMLIQVCLYFYCKFLWRCMKFVMRKLTGRCELQRICYGTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSDNPQHEEMLLKLWELLKPNTPLESRVSKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATVAQQVLSDSVHPKCSKFSKIEWEKKKMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
45	Ubiquitination	QRICYGTKPGASRTM EHHHCCCCCCCCCEE	36.77	-
129	Phosphorylation	LRREPYDSDNPQHEE HHCCCCCCCCHHHHH	33.18	27742792
212	Ubiquitination	PKCSKFSKIEWEKKK CCCCCCCCCHHHHHH	48.02	-
217	Ubiquitination	FSKIEWEKKKMDKAI CCCCHHHHHHHHHHH	59.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ELMD1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ELMD1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ELMD1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ELMD1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.