ELF2_MOUSE - dbPTM
ELF2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ELF2_MOUSE
UniProt AC Q9JHC9
Protein Name ETS-related transcription factor Elf-2
Gene Name Elf2 {ECO:0000312|MGI:MGI:1916507}
Organism Mus musculus (Mouse).
Sequence Length 593
Subcellular Localization Nucleus.
Protein Description Probably transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter..
Protein Sequence MASAVVDSGGSALELPSDGGENQEGGDTGPDCPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENSETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCISTPEFIHAAMRPDVITETVVEVSTEESEPMDASPIPTSPDSHEPMKKKKVGRKPKTQQSPVSNGSPELGIKKKAREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCPEDLAAAADDKSLERVSLSAESLLKAATAVRGGKNSSPLNCSRAEKGVARVVNITSPTHDGSSRSPTTTAPVSAAAAPRTVRVAMQVPVVMTSLGQKISAVAVQSVNAGTGSPLITSTSPASASSPKVVIQTVPTVMPASTENGDRITMQPAKIITIPATQLAQCQLQAKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSVPAQQASGQTPPRVISALLKGPEGKSEAKKQEHDVKTLQLVEEKGADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
47 (in isoform 3)Phosphorylation-55.5829514104
54 (in isoform 3)Phosphorylation-1.6425777480
56 (in isoform 3)Phosphorylation-17.3225777480
95PhosphorylationNAHCTDKTIEAAEAL
CCCCCHHHHHHHHHH		27.1928285833
107PhosphorylationEALLHMESPTCLRDS
HHHHCCCCCCCCCCC		20.2422942356
107 (in isoform 2)Phosphorylation-20.2429514104
109PhosphorylationLLHMESPTCLRDSRS
HHCCCCCCCCCCCCC		33.1926745281
114 (in isoform 2)Phosphorylation-28.3725777480
116 (in isoform 2)Phosphorylation-36.9325777480
182PhosphorylationKVGRKPKTQQSPVSN
CCCCCCCCCCCCCCC		40.1321082442
185PhosphorylationRKPKTQQSPVSNGSP
CCCCCCCCCCCCCCC		19.9022942356
188PhosphorylationKTQQSPVSNGSPELG
CCCCCCCCCCCCCCC		38.5722942356
191PhosphorylationQSPVSNGSPELGIKK
CCCCCCCCCCCCCCC		21.3222942356
304PhosphorylationVVIDDDKSETCPEDL
EEECCCCCCCCHHHH		45.1728973931
306PhosphorylationIDDDKSETCPEDLAA
ECCCCCCCCHHHHHH		40.2125266776
326PhosphorylationSLERVSLSAESLLKA
CCHHHCCCHHHHHHH		23.6028833060
343PhosphorylationAVRGGKNSSPLNCSR
HHHCCCCCCCCCCCH		36.5028066266
344PhosphorylationVRGGKNSSPLNCSRA
HHCCCCCCCCCCCHH		42.6828066266
362PhosphorylationVARVVNITSPTHDGS
EEEEEECCCCCCCCC		24.3723684622
363PhosphorylationARVVNITSPTHDGSS
EEEEECCCCCCCCCC		24.8126824392
365PhosphorylationVVNITSPTHDGSSRS
EEECCCCCCCCCCCC		32.1628833060
369PhosphorylationTSPTHDGSSRSPTTT
CCCCCCCCCCCCCCC		28.7430635358
370PhosphorylationSPTHDGSSRSPTTTA
CCCCCCCCCCCCCCC		42.1622942356
372PhosphorylationTHDGSSRSPTTTAPV
CCCCCCCCCCCCCCC		28.6626824392
374PhosphorylationDGSSRSPTTTAPVSA
CCCCCCCCCCCCCCC		37.7223684622
375O-linked_GlycosylationGSSRSPTTTAPVSAA
CCCCCCCCCCCCCCC		25.0963812141
375PhosphorylationGSSRSPTTTAPVSAA
CCCCCCCCCCCCCCC		25.0925266776
376O-linked_GlycosylationSSRSPTTTAPVSAAA
CCCCCCCCCCCCCCC		31.2921606357
376PhosphorylationSSRSPTTTAPVSAAA
CCCCCCCCCCCCCCC		31.2926643407
380PhosphorylationPTTTAPVSAAAAPRT
CCCCCCCCCCCCCCE		15.9026643407
419PhosphorylationSVNAGTGSPLITSTS
EECCCCCCCCEEECC		19.1728285833
423PhosphorylationGTGSPLITSTSPASA
CCCCCCEEECCCCCC		33.3725293948
424PhosphorylationTGSPLITSTSPASAS
CCCCCEEECCCCCCC		21.6425293948
425PhosphorylationGSPLITSTSPASASS
CCCCEEECCCCCCCC		30.0425293948
426PhosphorylationSPLITSTSPASASSP
CCCEEECCCCCCCCC		20.4525293948
429PhosphorylationITSTSPASASSPKVV
EEECCCCCCCCCCEE		31.8725293948
431PhosphorylationSTSPASASSPKVVIQ
ECCCCCCCCCCEEEE		44.6825293948
432PhosphorylationTSPASASSPKVVIQT
CCCCCCCCCCEEEEE		28.5826643407
496MethylationVGTPLAVRALTPVSI
ECCCEEEEECCCEEE		20.4824129315
499PhosphorylationPLAVRALTPVSIAHG
CEEEEECCCEEECCC		22.2127600695
502O-linked_GlycosylationVRALTPVSIAHGTPV
EEECCCEEECCCCCE		18.4363738343
513PhosphorylationGTPVMRLSVPAQQAS
CCCEEEEECCHHHHC		18.7126643407
520PhosphorylationSVPAQQASGQTPPRV
ECCHHHHCCCCCHHH		27.3926745281
523PhosphorylationAQQASGQTPPRVISA
HHHHCCCCCHHHHHH		38.4926745281
564PhosphorylationKGADGNKTVTHVVVV
CCCCCCCEEEEEEEE		34.3424759943
566PhosphorylationADGNKTVTHVVVVSA
CCCCCEEEEEEEEEC		17.7424759943
572PhosphorylationVTHVVVVSAPSAIAL
EEEEEEEECCCCEEC		23.8924759943
575PhosphorylationVVVVSAPSAIALPVT
EEEEECCCCEECCEE		31.8324759943
582PhosphorylationSAIALPVTMKTEGLV
CCEECCEEEECCCCE		15.8324759943
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ELF2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ELF2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ELF2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EPHB3_MOUSEEphb3physical
8954633
EPHB1_MOUSEEphb1physical
8954633
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ELF2_MOUSE

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Related Literatures of Post-Translational Modification

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