ELAV4_MOUSE - dbPTM
ELAV4_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ELAV4_MOUSE
UniProt AC Q61701
Protein Name ELAV-like protein 4
Gene Name Elavl4
Organism Mus musculus (Mouse).
Sequence Length 385
Subcellular Localization
Protein Description May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR. Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA (By similarity)..
Protein Sequence MEWNGLKMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationNGLKMIISTMEPQVS
CCEEEEHHCCCCCCC
15.6925293948
12PhosphorylationGLKMIISTMEPQVSN
CEEEEHHCCCCCCCC
18.3625293948
18PhosphorylationSTMEPQVSNGPTSNT
HCCCCCCCCCCCCCC
30.7125293948
22PhosphorylationPQVSNGPTSNTSNGP
CCCCCCCCCCCCCCC
35.6925293948
23PhosphorylationQVSNGPTSNTSNGPS
CCCCCCCCCCCCCCC
41.0425293948
25PhosphorylationSNGPTSNTSNGPSSN
CCCCCCCCCCCCCCC
24.2825293948
26PhosphorylationNGPTSNTSNGPSSNN
CCCCCCCCCCCCCCC
44.0025293948
30PhosphorylationSNTSNGPSSNNRNCP
CCCCCCCCCCCCCCC
47.2825293948
31PhosphorylationNTSNGPSSNNRNCPS
CCCCCCCCCCCCCCC
41.0625293948
38PhosphorylationSNNRNCPSPMQTGAA
CCCCCCCCCCCCCCC
34.8925521595
42PhosphorylationNCPSPMQTGAATDDS
CCCCCCCCCCCCCCC
23.6522324799
46PhosphorylationPMQTGAATDDSKTNL
CCCCCCCCCCCCCCE
39.5425159016
49PhosphorylationTGAATDDSKTNLIVN
CCCCCCCCCCCEEEE
44.1625159016
63PhosphorylationNYLPQNMTQEEFRSL
ECCCCCCCHHHHHHH
40.1430635358
86UbiquitinationSCKLVRDKITGQSLG
HCEEECCCCCCCCCC
31.44-
103UbiquitinationFVNYIDPKDAEKAIN
ECEECCHHHHHHHHH
66.86-
107UbiquitinationIDPKDAEKAINTLNG
CCHHHHHHHHHHHHC
57.18-
125PhosphorylationQTKTIKVSYARPSSA
EEEEEEEEEECCCCC
14.2019737024
126PhosphorylationTKTIKVSYARPSSAS
EEEEEEEEECCCCCC
15.0419737024
130PhosphorylationKVSYARPSSASIRDA
EEEEECCCCCCCCCC
32.7428066266
131PhosphorylationVSYARPSSASIRDAN
EEEECCCCCCCCCCC
28.8122817900
133PhosphorylationYARPSSASIRDANLY
EECCCCCCCCCCCEE
21.8028066266
146UbiquitinationLYVSGLPKTMTQKEL
EEECCCCCCCCHHHH
56.84-
146UbiquitinationLYVSGLPKTMTQKEL
EEECCCCCCCCHHHH
56.84-
149PhosphorylationSGLPKTMTQKELEQL
CCCCCCCCHHHHHHH
41.54-
151UbiquitinationLPKTMTQKELEQLFS
CCCCCCHHHHHHHHH
55.91-
151UbiquitinationLPKTMTQKELEQLFS
CCCCCCHHHHHHHHH
55.91-
165PhosphorylationSQYGRIITSRILVDQ
HHHHHHHHHHHHHHH
15.02-
211PhosphorylationSGATEPITVKFANNP
CCCCCCEEEEECCCC
28.49-
221UbiquitinationFANNPSQKSSQALLS
ECCCCCHHHHHHHHH
57.31-
221UbiquitinationFANNPSQKSSQALLS
ECCCCCHHHHHHHHH
57.31-
222PhosphorylationANNPSQKSSQALLSQ
CCCCCHHHHHHHHHH
21.7523527152
223PhosphorylationNNPSQKSSQALLSQL
CCCCHHHHHHHHHHH
26.8920415495
228PhosphorylationKSSQALLSQLYQSPN
HHHHHHHHHHHCCCC
20.9924759943
231PhosphorylationQALLSQLYQSPNRRY
HHHHHHHHCCCCCCC
10.1725521595
233PhosphorylationLLSQLYQSPNRRYPG
HHHHHHCCCCCCCCC
15.5825521595
237DimethylationLYQSPNRRYPGPLHH
HHCCCCCCCCCCCCH
48.95-
248MethylationPLHHQAQRFRLDNLL
CCCHHHHHHHHHHHH
22.97-
250DimethylationHHQAQRFRLDNLLNM
CHHHHHHHHHHHHHH
43.23-
262UbiquitinationLNMAYGVKRLMSGPV
HHHHHHHHHHHCCCC
35.14-
262UbiquitinationLNMAYGVKRLMSGPV
HHHHHHHHHHHCCCC
35.14-
327UbiquitinationQLFGPFGAVNNVKVI
HHHCCCCCCCCEEEE
10.97-
341UbiquitinationIRDFNTNKCKGFGFV
EEECCCCCCCCEEEE
34.97-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ELAV4_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference
248RMethylation

-

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ELAV4_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
G3BP1_MOUSEG3bp1physical
15086518

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ELAV4_MOUSE

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Related Literatures of Post-Translational Modification

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