dbPTM

EGG6_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	EGG6_CAEEL
UniProt AC	P90920
Protein Name	Leucine-rich repeat-containing protein egg-6
Gene Name	egg-6 {ECO:0000312\|EMBL:CAB03182.1, ECO:0000312\|WormBase:K07A12.2}
Organism	Caenorhabditis elegans.
Sequence Length	961
Subcellular Localization	Apical cell membrane Single-pass type I membrane protein .
Protein Description	Required for apical extracellular matrix organization and epithelial junction maintenance..
Protein Sequence	MRWLTLIAVAHLIAFLSSAEITCPRIPEKCDCKISKSMIILSCNGEDVKTIAQTVGTSQIDELHILNGTDVKIESLPFNGLRTIAILNSTLQSFSPTAWRHVEATIEHITINGNELKTVPVFGNLSTLMSMNLNSNQISSIPDKAFNGLSALTQLRLENNAICDFPPKSLDAVKASLVLLDVSGNCLDAIPAQILRNAANLMYLDLGSNNISEINNFELMNLPFLRELRVQNNTLRRIHPMAFMNVPQLQYLYLQDNIISTLDGNRLQGFKNLEVLDVSNNALYALPSLKDLPNLKQVRVDGNLITKIETLAFSNNPNLQLISVQNNNIVQISRNSFESLDKLVVLLVGNNSLAKIERGMFDGMKNLQQLSIRNNTLTALDASSFAQLAHLTTLDLGHNKIHDIEEGTFDKLSKLFWLDLSNNKISGFKTSVFKKKISNILLDGNQLICDESFNEFLTYLIANKVRTFLPFQQEIMCHGPEKYAGVRLKDLMMKKANETLSEGSRLLGVPQGSNQHSLLSSFLPSLGPLGTLNGAGGAAIPLVNTLTNTIPALRSIPGFGGNIPVGTGASSVPNKNLNDAIEGFTGPLVRFATGGQPVASDIEQLIRSIPNMVVNVPGFGDIDLSKMDPTMIQYVLNGGQIPGIDKATLDKIVKQTMNKMHTAAAANLAGNPVEGQEKVLPPLDKLPSGLVTQVMSGEPLPGLNENQTKIIMEYYTHQMPGMDGIPARPVESQGNTTANNMFNPAMFDLLKMLPPGYNLSKIPMEVIAAVTRGEVPDMRLLPEDLLEHFKQHTTSLTSMFAGATAKNISIEEILEKLPVFVRPELSTFVPYDINELTSEMVLEQEQNERHRNIRIITAIALAFVGAVTVVVIIFFVNYTKKQRRLRKSLVYRSSPSSSGSSGQNAANESGRSSAAPSPIRPPLMNIPKTPNNRTMESTFGQPQLCSTLLENPQAVSHRSRH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
893	Phosphorylation	RKSLVYRSSPSSSGS HHHHEECCCCCCCCC		30078680
894	Phosphorylation	KSLVYRSSPSSSGSS HHHEECCCCCCCCCC		30078680

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of EGG6_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of EGG6_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of EGG6_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of EGG6_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of EGG6_CAEEL

Related Literatures of Post-Translational Modification