dbPTM

EFGM_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	EFGM_CAEEL
UniProt AC	Q9XV52
Protein Name	Elongation factor G, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03061}
Gene Name	gfm-1
Organism	Caenorhabditis elegans.
Sequence Length	750
Subcellular Localization	Mitochondrion .
Protein Description	Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome..
Protein Sequence	MSPLGRFSAVAQSRRQLNNVLRRFASNEAPSSVVVPGVRPIERIRNIGISAHIDSGKTTVTERILYYAGRIDSMHEVRGKDDVGATMDFMDLERQRGITIQSAATYVDWHGTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCGVGGVQSQTFTVNRQLARYNVPFICFVNKMDRNGATPLKALDGLRNKLNHNAALIHLPIGKDSNFNGIVDLVEGHALYYEGEGGLIVRKDEIPKDLRVEAEDRRQELIEHIANVDETLGEMFLNDQTPNVQQIHEAIRRTVVKRAFVPVLSGSALKNKGVQTMINSVVKYLPDPSEVVNRATVKTETTGDEKGIILSPKRNNDKPFVGLAFKLEAGKYGQLTYFRVYQGQLSKGDTVYASRDGRKVRVQRLVRMHAADMEEITTAYAGDICATFGLDCHSGETFSTDQNLAPHCESMHIPEPVISMAIKPVNRKDADNFIKALTRFTKEDPTFRREYNQEAKETIVSGMGELHLEIYAQRMKSEYNCPVELGKPTVAYRECLGSPYKFHFRHKKQTGGQGQFGEIEGVIDPLPSDRNTVVEFSDETFGNNIPKNLFPALKKGLDAIVAEGPLIKSRIAGIHVRIQDGSTHAVDSTEIAMINTMQNMMRESFEKANWLLLEPIMKVEATVPTEFQGNVVTSLTQRNALITTTDSTEGYATVICEAPLSDMFGYTSELRSLTEGKGEFSMEYSRYAPTTLEAQDRVQAEWRQLHGIADPNEKGKKKKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of EFGM_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of EFGM_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of EFGM_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of EFGM_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of EFGM_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of EFGM_CAEEL

Related Literatures of Post-Translational Modification