EFCC1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EFCC1_HUMAN
• UniProt AC: Q9HA90
• Protein Name: EF-hand and coiled-coil domain-containing protein 1
• Gene Name: EFCC1
• Organism: Homo sapiens (Human).
• Sequence Length: 598
• Protein Sequence: MEPVSTGAEAGMEGAGGDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDCRGAGRLPRADFRALCAVLGLRAEGATTAGQAAGDGNSRDVTPGDAAAELATDGDSDTDEEARLALRAEPPELTFRQFHARLCGYFGTRAGPRLPRGALSEHIETQIRLRRPRRRRRPPCAPGPDSGPDCERVARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQASTHEMGHGGPEAAVRELRQAQGALAAAEARAGRLRRGQAEVRRRAEEARQVVLRSLHRVRELEALAQQVPGLQRWVRRLEAELQRYRSEDSQLPTPQLANPEPGDKSNEPEDAGTRDPDPTPEGAWQSDSSSGSRALDEVDEQLFRSVEGQAASDEEEVEEERWQEEKKTPAAEAKTLLARLSSCRGRCDDQTAEKLMTYFGHFGGANHAHTLGELEACIAMLVEQLRTQGCGGRTLGTSEEEAELQQKVEENEHLRLELQMVETERVRLSLLEEKLVDVLQLLQRLRDLNISKRALGKILLSTLDAFRDPTHEGRPSPAAILDALHQALAACQLLRRQPSAPASAAAALTNPLLVSC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
119	Phosphorylation	DAAAELATDGDSDTD HHHHHHCCCCCCCCC		28348404
123	Phosphorylation	ELATDGDSDTDEEAR HHCCCCCCCCCHHHH		26657352
125	Phosphorylation	ATDGDSDTDEEARLA CCCCCCCCCHHHHHH		27251275
141	Phosphorylation	RAEPPELTFRQFHAR HCCCCCCCHHHHHHH		24719451
241	Phosphorylation	GLWKSQASTHEMGHG CHHHCHHCCCCCCCC		-
394	Phosphorylation	SVEGQAASDEEEVEE HHCCCCCCCHHHHHH		26657352
410	Phosphorylation	RWQEEKKTPAAEAKT HHHHHHCCHHHHHHH		23090842
476	Phosphorylation	TQGCGGRTLGTSEEE HCCCCCCCCCCCHHH		29691806
479	Phosphorylation	CGGRTLGTSEEEAEL CCCCCCCCCHHHHHH		29691806
480	Phosphorylation	GGRTLGTSEEEAELQ CCCCCCCCHHHHHHH		26657352
511	Phosphorylation	ETERVRLSLLEEKLV HHHHHHHHHHHHHHH		24719451
533	Phosphorylation	RLRDLNISKRALGKI HHHHCCCCHHHHHHH		21815630
597	Phosphorylation	LTNPLLVSC------ HHCCCCCCC------		17929957

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EFCC1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EFCC1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EFCC1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of EFCC1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.