EFC11_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EFC11_HUMAN
• UniProt AC: Q9BUY7
• Protein Name: EF-hand calcium-binding domain-containing protein 11
• Gene Name: EFCAB11
• Organism: Homo sapiens (Human).
• Sequence Length: 163
• Protein Sequence: MFFSEARARSRTWEASPSEHRKWVEVFKACDEDHKGYLSREDFKTAVVMLFGYKPSKIEVDSVMSSINPNTSGILLEGFLNIVRKKKEAQRYRNEVRHIFTAFDTYYRGFLTLEDFKKAFRQVAPKLPERTVLEVFREVDRDSDGHVSFRDFEYALNYGQKEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MFFSEARARSR ----CCCCHHHHHHC	21.05	26552605
10	Phosphorylation	FSEARARSRTWEASP CCHHHHHHCCCCCCH	32.83	26552605
12	Phosphorylation	EARARSRTWEASPSE HHHHHHCCCCCCHHH	28.98	-
18	Phosphorylation	RTWEASPSEHRKWVE CCCCCCHHHHHHHHH	43.47	19845377
28	Ubiquitination	RKWVEVFKACDEDHK HHHHHHHHHCCCCCC	53.96	29967540
45	Phosphorylation	LSREDFKTAVVMLFG CCHHHHHHHHHHHHC	25.36	29759185
53	Phosphorylation	AVVMLFGYKPSKIEV HHHHHHCCCCCCEEC	16.64	29759185
54 (in isoform 4)	Ubiquitination	-	43.10	21890473
56	Phosphorylation	MLFGYKPSKIEVDSV HHHCCCCCCEECCHH	41.96	29759185
65	Phosphorylation	IEVDSVMSSINPNTS EECCHHHHHCCCCCC	26.38	23684312
66	Phosphorylation	EVDSVMSSINPNTSG ECCHHHHHCCCCCCH	14.32	23684312
69	Ubiquitination	SVMSSINPNTSGILL HHHHHCCCCCCHHHH	43.75	21890473
70	Ubiquitination	VMSSINPNTSGILLE HHHHCCCCCCHHHHH	42.25	22817900
71	Phosphorylation	MSSINPNTSGILLEG HHHCCCCCCHHHHHH	29.59	23684312
92	Phosphorylation	KKKEAQRYRNEVRHI HHHHHHHHHHHHHHH	13.00	-
93 (in isoform 3)	Ubiquitination	-	34.71	21890473
93 (in isoform 2)	Ubiquitination	-	34.71	21890473
93	Ubiquitination	KKEAQRYRNEVRHIF HHHHHHHHHHHHHHH	34.71	21890473
94	Ubiquitination	KEAQRYRNEVRHIFT HHHHHHHHHHHHHHH	43.08	22817900
113	Ubiquitination	YYRGFLTLEDFKKAF HHCCCCCHHHHHHHH	6.90	-
117 (in isoform 1)	Ubiquitination	-	56.36	21890473
117	Ubiquitination	FLTLEDFKKAFRQVA CCCHHHHHHHHHHHH	56.36	22817900
117	Ubiquitination	FLTLEDFKKAFRQVA CCCHHHHHHHHHHHH	56.36	21890473
117	Ubiquitination	FLTLEDFKKAFRQVA CCCHHHHHHHHHHHH	56.36	21890473
118	Ubiquitination	LTLEDFKKAFRQVAP CCHHHHHHHHHHHHC	53.39	22817900
137 (in isoform 2)	Ubiquitination	-	48.48	21890473
161 (in isoform 1)	Ubiquitination	-	51.77	21890473
161	Ubiquitination	YALNYGQKEA----- HHHHCCCCCC-----	51.77	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EFC11_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EFC11_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EFC11_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of EFC11_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.