EF1G_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EF1G_MOUSE
• UniProt AC: Q9D8N0
• Protein Name: Elongation factor 1-gamma
• Gene Name: Eef1g
• Organism: Mus musculus (Mouse).
• Sequence Length: 437
• Protein Description: Probably plays a role in anchoring the complex to other cellular components..
• Protein Sequence: MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGTFQHVGKAVNQGKIFK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAGTLYTY ------CCCCCEECC	18.01	-
7	Phosphorylation	-MAAGTLYTYPENWR -CCCCCEECCCCCHH	12.22	29514104
17	Acetylation	PENWRAFKALIAAQY CCCHHHHHHHHHHHH	41.10	22826441
33	Phosphorylation	GAQVRVLSAPPHFHF CCEEEEEECCCCCCC	35.55	28507225
43	Phosphorylation	PHFHFGQTNRTPEFL CCCCCCCCCCCHHHH	27.35	25168779
46	Phosphorylation	HFGQTNRTPEFLRKF CCCCCCCCHHHHHHC	29.28	26824392
128	Phosphorylation	MHHNKQATENAKEEV CCCCHHHHHHHHHHH	27.55	-
132	Acetylation	KQATENAKEEVKRIL HHHHHHHHHHHHHHH	67.02	23864654
132	Succinylation	KQATENAKEEVKRIL HHHHHHHHHHHHHHH	67.02	23954790
136	Acetylation	ENAKEEVKRILGLLD HHHHHHHHHHHHHHH	36.68	23201123
147	Malonylation	GLLDTHLKTRTFLVG HHHHHCCCCCEEECC	28.49	26320211
147	Ubiquitination	GLLDTHLKTRTFLVG HHHHHCCCCCEEECC	28.49	-
147	Acetylation	GLLDTHLKTRTFLVG HHHHHCCCCCEEECC	28.49	23806337
179	Phosphorylation	YKQVLEPSFRQAFPN HHHHHCHHHHHHCCC	24.56	29472430
194	S-nitrosocysteine	TNRWFLTCINQPQFR CCCEEEHHCCCHHHH	2.75	-
194	S-nitrosylation	TNRWFLTCINQPQFR CCCEEEHHCCCHHHH	2.75	21278135
194	S-palmitoylation	TNRWFLTCINQPQFR CCCEEEHHCCCHHHH	2.75	28526873
208	Ubiquitination	RAILGEVKLCEKMAQ HHHHHHHHHHHHHHH	43.02	-
208	Malonylation	RAILGEVKLCEKMAQ HHHHHHHHHHHHHHH	43.02	26320211
210	Glutathionylation	ILGEVKLCEKMAQFD HHHHHHHHHHHHHHC	3.81	24333276
212	Malonylation	GEVKLCEKMAQFDAK HHHHHHHHHHHHCHH	38.24	26320211
212	Ubiquitination	GEVKLCEKMAQFDAK HHHHHHHHHHHHCHH	38.24	-
212	Acetylation	GEVKLCEKMAQFDAK HHHHHHHHHHHHCHH	38.24	23806337
219	Malonylation	KMAQFDAKKFAESQP HHHHHCHHHHHHHCC	50.71	26320211
219	Succinylation	KMAQFDAKKFAESQP HHHHHCHHHHHHHCC	50.71	23954790
220	Malonylation	MAQFDAKKFAESQPK HHHHCHHHHHHHCCC	52.07	26320211
220	Acetylation	MAQFDAKKFAESQPK HHHHCHHHHHHHCCC	52.07	23806337
220	Ubiquitination	MAQFDAKKFAESQPK HHHHCHHHHHHHCCC	52.07	-
224	Phosphorylation	DAKKFAESQPKKDTP CHHHHHHHCCCCCCC	48.64	-
227	Malonylation	KFAESQPKKDTPRKE HHHHHCCCCCCCCCC	56.49	26320211
227	Ubiquitination	KFAESQPKKDTPRKE HHHHHCCCCCCCCCC	56.49	-
253	Malonylation	AERKEEKKAAAPAPE HHHHHHHHHCCCCCH	46.68	26320211
266	Glutathionylation	PEEEMDECEQALAAE CHHHHHHHHHHHHHC	4.02	24333276
266	S-nitrosylation	PEEEMDECEQALAAE CHHHHHHHHHHHHHC	4.02	24926564
266	S-nitrosocysteine	PEEEMDECEQALAAE CHHHHHHHHHHHHHC	4.02	-
275	Malonylation	QALAAEPKAKDPFAH HHHHHCCCCCCCCCC	60.62	26320211
277	Malonylation	LAAEPKAKDPFAHLP HHHCCCCCCCCCCCC	72.55	26320211
277	Ubiquitination	LAAEPKAKDPFAHLP HHHCCCCCCCCCCCC	72.55	-
285	Acetylation	DPFAHLPKSTFVLDE CCCCCCCCCCEEHHH	69.37	23236377
286	Phosphorylation	PFAHLPKSTFVLDEF CCCCCCCCCEEHHHH	25.74	24899341
294	Succinylation	TFVLDEFKRKYSNED CEEHHHHHHHCCCCC	46.03	23806337
294	Acetylation	TFVLDEFKRKYSNED CEEHHHHHHHCCCCC	46.03	23806337
294	Ubiquitination	TFVLDEFKRKYSNED CEEHHHHHHHCCCCC	46.03	-
297	Phosphorylation	LDEFKRKYSNEDTLS HHHHHHHCCCCCCHH	22.29	26745281
298	Phosphorylation	DEFKRKYSNEDTLSV HHHHHHCCCCCCHHH	36.46	26239621
302	Phosphorylation	RKYSNEDTLSVALPY HHCCCCCCHHHHHHH	18.11	23984901
304	Phosphorylation	YSNEDTLSVALPYFW CCCCCCHHHHHHHHH	13.87	26745281
326	Phosphorylation	WSLWYAEYRFPEELT CEEEEEEECCCHHHH	14.91	24511133
387	Phosphorylation	QELAFPLSPDWQVDY EEEEEECCCCCEEEH	22.50	26643407
401	Acetylation	YESYTWRKLDPGSEE HHEEEEEECCCCCHH	49.13	23806337
406	Phosphorylation	WRKLDPGSEETQTLV EEECCCCCHHHHHHH	37.33	28464351
428	Acetylation	GTFQHVGKAVNQGKI CCHHHHHHHHHCCCC	48.34	22826441
434	Succinylation	GKAVNQGKIFK---- HHHHHCCCCCC----	34.89	23954790
434	Malonylation	GKAVNQGKIFK---- HHHHHCCCCCC----	34.89	26320211
434	Acetylation	GKAVNQGKIFK---- HHHHHCCCCCC----	34.89	23806337
434	N6-malonyllysine	GKAVNQGKIFK---- HHHHHCCCCCC----	34.89	-
434	Ubiquitination	GKAVNQGKIFK---- HHHHHCCCCCC----	34.89	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EF1G_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EF1G_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EF1G_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of EF1G_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.