EBPL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EBPL_HUMAN
• UniProt AC: Q9BY08
• Protein Name: Emopamil-binding protein-like
• Gene Name: EBPL
• Organism: Homo sapiens (Human).
• Sequence Length: 206
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Description: Does not possess sterol isomerase activity and does not bind sigma ligands..
• Protein Sequence: MGAEWELGAEAGGSLLLCAALLAAGCALGLRLGRGQGAADRGALIWLCYDALVHFALEGPFVYLSLVGNVANSDGLIASLWKEYGKADARWVYFDPTIVSVEILTVALDGSLALFLIYAIVKEKYYRHFLQITLCVCELYGCWMTFLPEWLTRSPNLNTSNWLYCWLYLFFFNGVWVLIPGLLLWQSWLELKKMHQKETSSVKKFQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
86	Ubiquitination	SLWKEYGKADARWVY HHHHHHCCCCCEEEE	42.04	-
199	Phosphorylation	KKMHQKETSSVKKFQ HHHHHHCCCCCCCCC	33.08	29083192
200	Phosphorylation	KMHQKETSSVKKFQ- HHHHHCCCCCCCCC-	33.94	29083192
201	Phosphorylation	MHQKETSSVKKFQ-- HHHHCCCCCCCCC--	45.43	29083192

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EBPL_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EBPL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EBPL_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of EBPL_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.