DZIP1_HUMAN - dbPTM
DZIP1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DZIP1_HUMAN
UniProt AC Q86YF9
Protein Name Zinc finger protein DZIP1
Gene Name DZIP1
Organism Homo sapiens (Human).
Sequence Length 867
Subcellular Localization Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . In testis, it is predominantly nuclear, with some cytoplasmic localization in spermatogonia. Colocalize
Protein Description May participate in spermatogenesis via its interaction with DAZ. [PubMed: 15081113 Has a role in primary cilium formation]
Protein Sequence MQAEAADWFSSMPFQKHVYYPLASGPEGPDVAVAAAAAGAASMACAPPSAASGPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSGVDPVLLKLIRLAQFTIEYLLHSQEFLTSQLHTLEERLRLSHCDGEQSKKLLTKQAGEIKTLKEECKRRKKMISTQQLMIEAKANYYQCHFCDKAFMNQAFLQSHIQRRHTEENSHFEYQKNAQIEKLRSEIVVLKEELQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFMKEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDRSPYPQDFHNVMQLLDSQESKWTARVQAIHQEHKKEKGRLLSHIEKLRTSMIDDLNASNVFYKKRIEELGQRLQEQNELIITQRQQIKDFTCNPLNSISEPKGNPLAWQAFESQPAAPAVPMNAPALHTLETKSSLPMVHEQAFSSHILEPIEELSEEEKGRENEQKLNNNKMHLRKALKSNSSLTKGLRTMVEQNLMEKLETLGINADIRGISSDQLHRVLKSVESERHKQEREIPNFHQIREFLEHQVSCKIEEKALLSSDQCSVSQMDTLSTGEVPKMIQLPSKNRQLIRQKAVSTDRTSVPKIKKNVMEDPFPRKSSTITTPPFSSEEEQEDDDLIRAYASPGPLPVPPPQNKGSFGKNTVKSDADGTEGSEIEDTDDSPKPAGVAVKTPTEKVEKMFPHRKNVNKPVGGTNVPEMFIKKEELQELKCADVEDEDWDISSLEEEISLGKKSGKEQKEPPPAKNEPHFAHVLNAWGAFNPKGPKGEGLQENESSTLKSSLVTVTDWSDTSDV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
66PhosphorylationQFRPRLESVDWRRLS
CCCCCCCCCCCCCCC		29.9329449344
178UbiquitinationKTLKEECKRRKKMIS
HHHHHHHHHHHHHCH		59.52-
185PhosphorylationKRRKKMISTQQLMIE
HHHHHHCHHHHHHHH		19.3729978859
186PhosphorylationRRKKMISTQQLMIEA
HHHHHCHHHHHHHHH		14.9229978859
272PhosphorylationAVRFSKEYEMQKTKE
HHHCCHHHHCHHCCH		22.0429496907
278AcetylationEYEMQKTKEEDFLKL
HHHCHHCCHHHHHHH		67.177695429
324PhosphorylationSKNSALEYQLSEIQK
CCCCHHHHHHHHHHH		18.6629083192
327PhosphorylationSALEYQLSEIQKSNM
CHHHHHHHHHHHHCC		19.6829083192
332PhosphorylationQLSEIQKSNMQIKSN
HHHHHHHHCCHHHHH		22.5929083192
338PhosphorylationKSNMQIKSNIGTLKD
HHCCHHHHHCCCCCC		35.0027174698
342PhosphorylationQIKSNIGTLKDAHEF
HHHHHCCCCCCHHHH		27.1727174698
410PhosphorylationMIDDLNASNVFYKKR
HHCCCCCCCHHHHHH		32.24-
414PhosphorylationLNASNVFYKKRIEEL
CCCCCHHHHHHHHHH		16.0025884760
533PhosphorylationHLRKALKSNSSLTKG
HHHHHHHCCCHHHHH		42.6829978859
535PhosphorylationRKALKSNSSLTKGLR
HHHHHCCCHHHHHHH		33.5429978859
536PhosphorylationKALKSNSSLTKGLRT
HHHHCCCHHHHHHHH		44.2929978859
538PhosphorylationLKSNSSLTKGLRTMV
HHCCCHHHHHHHHHH		25.6429978859
566PhosphorylationNADIRGISSDQLHRV
CCCCCCCCHHHHHHH		30.5928857561
638PhosphorylationPKMIQLPSKNRQLIR
CCCEECCCCCHHHHH		51.6724719451
650O-linked_GlycosylationLIRQKAVSTDRTSVP
HHHHHHHCCCCCCCH		29.4730620550
672PhosphorylationEDPFPRKSSTITTPP
CCCCCCCCCCCCCCC		33.7127732954
673PhosphorylationDPFPRKSSTITTPPF
CCCCCCCCCCCCCCC		27.1927732954
674PhosphorylationPFPRKSSTITTPPFS
CCCCCCCCCCCCCCC		29.4527732954
676PhosphorylationPRKSSTITTPPFSSE
CCCCCCCCCCCCCCH		33.0827732954
677PhosphorylationRKSSTITTPPFSSEE
CCCCCCCCCCCCCHH		25.7227732954
681PhosphorylationTITTPPFSSEEEQED
CCCCCCCCCHHHHCC		42.4827732954
682PhosphorylationITTPPFSSEEEQEDD
CCCCCCCCHHHHCCC		49.7827732954
695PhosphorylationDDDLIRAYASPGPLP
CCHHHHHHCCCCCCC		9.5827642862
724PhosphorylationVKSDADGTEGSEIED
CCCCCCCCCCCCCCC		37.4127732954
727PhosphorylationDADGTEGSEIEDTDD
CCCCCCCCCCCCCCC		29.2122617229
732PhosphorylationEGSEIEDTDDSPKPA
CCCCCCCCCCCCCCC		28.9927732954
735PhosphorylationEIEDTDDSPKPAGVA
CCCCCCCCCCCCCEE		37.3227732954
802PhosphorylationSSLEEEISLGKKSGK
HHHHHHHHHCCCCCC		34.0626437602
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DZIP1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DZIP1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DZIP1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of DZIP1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DZIP1_HUMAN

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Related Literatures of Post-Translational Modification

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