DZAN1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DZAN1_HUMAN
• UniProt AC: Q9NVP4
• Protein Name: Double zinc ribbon and ankyrin repeat-containing protein 1
• Gene Name: DZANK1
• Organism: Homo sapiens (Human).
• Sequence Length: 752
• Protein Sequence: MTAGSVCVPQIIPLRVPQPGKANHEIDNNTLLEMKSDTPDVNIYYTLDGSKPEFLKRIGYGENNTFKYIKPITLPDGKIQVKAIAVSKDCRQSGIVTKVFHVDYEPPNIVSPEDNVENVLKDSSRQEFKNGFVGSKLKKKYKNSENQRSWNVNLRKFPESPLEIPAYGGGSGSRPPTRQSQSPGFAHVSGQKCLTSTEIMRIQRETDFLKCAHCLAPRPSDPFARFCQECGSPVPPIFGCRLPPPEGAQMGLCAECRSLVPMNTPICVVCEAPLALQLQPQASLHLKEKVICRACGTGNPAHLRYCVTCEGALPSSQESMCSGDKAPPPPTQKGGTISCYRCGRWNLWEASFCGWCGAMLGIPAGCSVCPKCGASNHLSARFCGSCGICVKSLVKLSLDRSLALAAEEPRPFSESLNIPLPRSDVGTKRDIGTQTVGLFYPSGKLLAKKEQELASQKQRQEKMSDHKPLLTAISPGRGYWRRQLDHISAHLRCYAQNNPEFRALIAEPRMGKLISATVHEDGCEVSIRLNYSQVSNKNLYLNKAVNFSDHLLSSAAEGDGGLCGSRSSWVSDYSQSTSDTIEKIKRIKNFKTKTFQEKKEQLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAAKFGQGLEDQLAQTRSLSLDDC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTAGSVCVP ------CCCCCCCCC	39.46	25332170
9 (in isoform 2)	Phosphorylation	-	17.96	20068231
111	Phosphorylation	YEPPNIVSPEDNVEN CCCCCCCCCCCCHHH	20.83	27966365
121	Ubiquitination	DNVENVLKDSSRQEF CCHHHHHHHCCCHHH	51.81	-
160	Phosphorylation	NLRKFPESPLEIPAY CCCCCCCCCCCCCCC	34.71	-
182	Phosphorylation	PPTRQSQSPGFAHVS CCCCCCCCCCCCCCC	32.03	20068231
260	Phosphorylation	CAECRSLVPMNTPIC CHHHHHCCCCCCCEE	4.45	18669648
305	Phosphorylation	GNPAHLRYCVTCEGA CCHHHHEEEEECCCC	9.53	-
308	Phosphorylation	AHLRYCVTCEGALPS HHHEEEEECCCCCCC	10.98	-
433	Phosphorylation	GTKRDIGTQTVGLFY CCCCCCCCCEEEEEC	22.77	18669648
448	Ubiquitination	PSGKLLAKKEQELAS CCHHHHHHHHHHHHH	57.73	-
455	Phosphorylation	KKEQELASQKQRQEK HHHHHHHHHHHHHHH	51.00	-
531	Phosphorylation	EVSIRLNYSQVSNKN EEEEEEECCCCCCCC	12.69	22461510
532	Phosphorylation	VSIRLNYSQVSNKNL EEEEEECCCCCCCCE	24.04	22461510
571	Phosphorylation	GSRSSWVSDYSQSTS CCCHHHHCCCCCCCH	25.27	-
616	Phosphorylation	LLKEVGPTGEGRVSV EEEECCCCCCCCHHH	41.77	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DZAN1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DZAN1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DZAN1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of DZAN1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.