dbPTM

DUT_HHV11 - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DUT_HHV11
UniProt AC	P10234
Protein Name	Deoxyuridine 5'-triphosphate nucleotidohydrolase {ECO:0000255\|HAMAP-Rule:MF_04031}
Gene Name	DUT {ECO:0000255\|HAMAP-Rule:MF_04031}
Organism	Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1).
Sequence Length	371
Subcellular Localization
Protein Description	Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA..
Protein Sequence	MSQWGSGAILVQPDSLGRGYDGDWHTAVATRGGGVVQLNLVNRRAVAFMPKVSGDSGWAVGRVSLDLRMAMPADFCAIIHAPALASPGHHVILGLIDSGYRGTVMAVVVAPKRTREFAPGTLRVDVTFLDILATPPALTEPISLRQFPQLAPPPPTGAGIREDPWLEGALGAPSVTTALPARRRGRSLVYAGELTPVQTEHGDGVREAIAFLPKREEDAGFDIVVRRPVTVPANGTTVVQPSLRMLHADAGPAACYVLGRSSLNARGLLVVPTRWLPGHVCAFVVYNLTGVPVTLEAGAKVAQLLVAGADALPWIPPDNFHGTKALRNYPRGVPDSTAEPRNPPLLVFTNEFDAEAPPSERGTGGFGSTGI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of DUT_HHV11 !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DUT_HHV11 !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DUT_HHV11 !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DUT_HHV11 !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DUT_HHV11 !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DUT_HHV11

Related Literatures of Post-Translational Modification