DSLE_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DSLE_ARATH
• UniProt AC: Q9M2N5
• Protein Name: Zinc finger BED domain-containing protein DAYSLEEPER
• Gene Name: HAT
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 696
• Subcellular Localization: Nucleus .
• Protein Description: Transposase-like protein that is essential for plant growth and development. Binds the promoter region of the DNA helicase KU70 and genes involved in chromatin remodeling. May regulate global gene expression by recruiting other cellular factors..
• Protein Sequence: MEVYNDDTEMRSPETQPIKETALEVYNDTAEIRSPETQPIEETALEVYNDTEMVSPETQPIKRRKKKSMVWEHFTIEAVEPNCRRAFCKGCNQSFAYSNGNKVAGTSHLKRHIFKGTCPALIHTHDNDNNPLMSTPYTPKTDTPRRRYRSQNNASPYVAFNQDKCRQEIAKMIIMHDYPLHMVQHPGFVSFVQSIQPHFDAVSFNNVQGDCVATYLAEKQNVMKSLEGIPGRFCLTLDFWTSKLTLGYVFITAHYIDSDWKIQKKLLNVLMESYPEADEALSLAVANCVSEWGLEGKLFNVTFNHPASNSAVENIRPQLCIKNPGILDGQLVIGNCVARTFGSLAKDVLEKGKDVIKNIRDSVKHVKTSESHEERFTELKEQLQVPSEKVLSLDDQTQWNTTYMMLVAASELKEVFSCLDTADPDYKKPPSAEDWRHVEALCTFLKPLFEAVSTLQSTGNPSAVTFFHEVWKTQSDLSRAIAGEDPFVTGIAKTMQEKVDKYWRDCSLVLAMAVVMDPRFKMKLVEFSFSKIFGEDAGKNIKTVDDGIHELFTEYMALPSPQNTTSEGGKADGLSDFDTYIMETTGQNLKSELDQYLDETLLPRVQEFDVLDWWKQNKLKYPTLSKMARDILSIPVSAAAFDYVFDMEPREMDEYKTSLRPETVEALICAREWLLESNASSSAAAQNASATIKSEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MEVYNDDTEMRSPET CCCCCCCCCCCCCCC		30589143
12	Phosphorylation	NDDTEMRSPETQPIK CCCCCCCCCCCCCCC		27532006
15	Phosphorylation	TEMRSPETQPIKETA CCCCCCCCCCCCHHH		30407730
21	Phosphorylation	ETQPIKETALEVYND CCCCCCHHHHHHHCC		23776212
26	Phosphorylation	KETALEVYNDTAEIR CHHHHHHHCCCCCCC		23776212
29	Phosphorylation	ALEVYNDTAEIRSPE HHHHHCCCCCCCCCC		23776212
34	Phosphorylation	NDTAEIRSPETQPIE CCCCCCCCCCCCCCC		23776212
37	Phosphorylation	AEIRSPETQPIEETA CCCCCCCCCCCCCHH		23776212
43	Phosphorylation	ETQPIEETALEVYND CCCCCCCHHHHHHCC		23776212
48	Phosphorylation	EETALEVYNDTEMVS CCHHHHHHCCCCCCC		23776212
51	Phosphorylation	ALEVYNDTEMVSPET HHHHHCCCCCCCCCC		30407730
55	Phosphorylation	YNDTEMVSPETQPIK HCCCCCCCCCCCCCC		30407730
58	Phosphorylation	TEMVSPETQPIKRRK CCCCCCCCCCCCCCC		25561503
150	Phosphorylation	TPRRRYRSQNNASPY CCCHHHHCCCCCCCC		25561503
155	Phosphorylation	YRSQNNASPYVAFNQ HHCCCCCCCCCCCCH		27531888
157	Phosphorylation	SQNNASPYVAFNQDK CCCCCCCCCCCCHHH		19880383
528	Phosphorylation	KMKLVEFSFSKIFGE HEEEEEEHHHHHHCC		19880383
543	Phosphorylation	DAGKNIKTVDDGIHE CCCCCCEECCHHHHH		23776212
553	Phosphorylation	DGIHELFTEYMALPS HHHHHHHHHHHCCCC		23776212
555	Phosphorylation	IHELFTEYMALPSPQ HHHHHHHHHCCCCCC		23776212
560	Phosphorylation	TEYMALPSPQNTTSE HHHHCCCCCCCCCCC		23776212
564	Phosphorylation	ALPSPQNTTSEGGKA CCCCCCCCCCCCCCC		23776212
565	Phosphorylation	LPSPQNTTSEGGKAD CCCCCCCCCCCCCCC		23776212
566	Phosphorylation	PSPQNTTSEGGKADG CCCCCCCCCCCCCCC		23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DSLE_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DSLE_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DSLE_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of DSLE_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.