dbPTM

DRS7B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DRS7B_MOUSE
UniProt AC	Q99J47
Protein Name	Dehydrogenase/reductase SDR family member 7B
Gene Name	Dhrs7b
Organism	Mus musculus (Mouse).
Sequence Length	323
Subcellular Localization	Endoplasmic reticulum membrane Single-pass type II membrane protein.
Protein Description	Putative oxidoreductase..
Protein Sequence	MISPSFRKGMLKERVMDLASQTTILPLLFGCLGIFSLFRLLQRIRSKAYLRNAVVVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQGQTHQPFVVTFDLADPGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEANIKVTVISPGYIHTNLSVNAVTADGSRYGALDKNTAQGRSAAEVAQDVFDAVGKKKKDVLLTDFVPSMAVYIRTLAPGLFFRIMASRARKERKSKSS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MISPSFRKGM -----CCCHHHHHCC	17.13	28066266
5	Phosphorylation	---MISPSFRKGMLK ---CCCHHHHHCCHH	30.78	28066266
87	Ubiquitination	VLCGRNVKALEELSR EECCCCHHHHHHHHH	51.29	22790023
159	Ubiquitination	TIVDVDRKVMEINYF EEEECCCCEEEEECC	41.28	22790023
198	Phosphorylation	SSIQGKISIPFRSAY EEECCEEECCCHHHC	27.91	20469934
203	Phosphorylation	KISIPFRSAYSASKH EEECCCHHHCCCCHH	31.75	22871156
205	Phosphorylation	SIPFRSAYSASKHAT ECCCHHHCCCCHHHH	13.15	22871156
209	Acetylation	RSAYSASKHATQAFF HHHCCCCHHHHHHHH	36.65	22826441
259	Acetylation	SRYGALDKNTAQGRS CEECCCCCCCCCCCC	57.98	23954790
259	Malonylation	SRYGALDKNTAQGRS CEECCCCCCCCCCCC	57.98	26320211

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DRS7B_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DRS7B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DRS7B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DRS7B_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DRS7B_MOUSE

Related Literatures of Post-Translational Modification