dbPTM

DRE1_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DRE1_CAEEL
UniProt AC	Q94251
Protein Name	F-box protein dre-1 {ECO:0000305}
Gene Name	dre-1 {ECO:0000312\|WormBase:K04A8.6a}
Organism	Caenorhabditis elegans.
Sequence Length	936
Subcellular Localization	Nucleus . Cytoplasm .
Protein Description	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins including blmp-1. [PubMed: 17336909]
Protein Sequence	MSSSSSPFFHPPPQQVMDDTTQQSPSYSQNSNSPSQHTFESMEPAAGGSTSMRYSPSGSSEADNPTLGLFSAQASYPYSLRKRRPCLTKDEDLCFPITAATADETPQPTMKKFKLECLSPGEARDFSIEDESGTNLEAKMETTECEPEEEEAVEEEDQQDHINRLPEELLLKVFSFLPDKSLLACSSVSYRFNQISNSHEVWKELYCNLYDYRIPLFHPSHAKFEFREQSRWRDGNPWKESHRQLHHGVHVMKEPRVNLRSVNYRCFDQIEKAQSFLEEDEYREKLIFLHTGVHEPIDTILINTDVQIIGASDSRDITSSVVLEGSKNTALTFTDGSANAYFGFITVRFRADPVCRQQPQIAQQAQQMNHFYSILVTDKDAMPYIERCDITSKVGNGAAVCVKKSAAPKFKYCTVLDCENVGIYITDNATGHYEHCEIARNTLAGVWVKNHANPYFRKCTIHSGKDVGVFTFEHGQGYFEKCNIHSNRISGIEVKNSANPVVIRCEVHHGYTGGIYVHERGRGQFMENRIYANAYAGIWITSHSDPTIRKNEIFTGQQGGVYIFGEGRGLIEQNNIYGNALAGIQIRSQSDPIVRLNKIHDGLHGGIYVHEKGRGLIEENEVYGNTLAGIWVTTGSSPILRKNRIHSGKQVGVYFYDQGHGLLEENDIFNHLYSGVQIRTGSNPKITRNKIWGGQNGGVLVYNGGKGCLEDNEIFDNAMAGVWIKTDSEPTLRRNKIYDGRDGGVCIFNRGKGLLEDNEIFRNAQAGVLISTESNPTLRRNRVFDGKSAGIEITNGATATLEENQLFRNKYGGLCVATGVTPVQRGNRIYDNHDTISRAIKTGLCLFKVSSNNSFPMHNFYRCTTCNTTERNAICTNCIRTCHRGHSVELVRFDRFFCDCGAGTLERHCHLQNVPRDNDTVYDSATPISTETGTEI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of DRE1_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DRE1_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DRE1_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DRE1_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DRE1_CAEEL

Related Literatures of Post-Translational Modification