DPYL4_RAT - dbPTM
DPYL4_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DPYL4_RAT
UniProt AC Q62951
Protein Name Dihydropyrimidinase-related protein 4
Gene Name Dpysl4
Organism Rattus norvegicus (Rat).
Sequence Length 564
Subcellular Localization Cytoplasm.
Protein Description Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)..
Protein Sequence IPRITSDRLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYITKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGINGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGMPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVMLPAKPGSGTQARASCPGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNITSLS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
6Phosphorylation--IPRITSDRLLIKG
--CCCCCCCCEEEEC		20.5425403869
12UbiquitinationTSDRLLIKGGKIVND
CCCCEEEECCEECCC		62.67-
12AcetylationTSDRLLIKGGKIVND
CCCCEEEECCEECCC		62.6713580041
93PhosphorylationKAALAGGTTMILDHV
HHHHCCCCEEEECCC		16.57-
94PhosphorylationAALAGGTTMILDHVF
HHHCCCCEEEECCCC		12.89-
243PhosphorylationKQANCPLYITKVMSK
HHCCCCEEEEECCCC		7.5330181290
245PhosphorylationANCPLYITKVMSKGA
CCCCEEEEECCCCCH		12.2030181290
249PhosphorylationLYITKVMSKGAADMV
EEEEECCCCCHHHHH		30.8130181290
250SuccinylationYITKVMSKGAADMVA
EEEECCCCCHHHHHH		34.18-
337UbiquitinationTAQKAVGKDNFTLIP
CCHHHHCCCCEEECC		42.79-
415UbiquitinationATKVISAKSHNLNVE
CCEEEEEECCCCCCE		45.52-
423PhosphorylationSHNLNVEYNIFEGVE
CCCCCCEEEEEECCC		14.85-
464UbiquitinationAGRFIPRKTFPDFVY
CCCCCCCCCCCHHHH		49.52-
491PhosphorylationHGVPRGLYDGPVHEV
HCCCCCCCCCCCEEE		22.98-
503UbiquitinationHEVMLPAKPGSGTQA
EEEEEECCCCCCCCC		48.23-
513PhosphorylationSGTQARASCPGKISV
CCCCCCCCCCCCCCC		18.45-
529PhosphorylationPVRNLHQSGFSLSGS
CCCCCEECCCCCCCC		30.9327097102
532PhosphorylationNLHQSGFSLSGSQAD
CCEECCCCCCCCCHH		25.7527097102
534PhosphorylationHQSGFSLSGSQADDH
EECCCCCCCCCHHHH		34.8927097102
536PhosphorylationSGFSLSGSQADDHIA
CCCCCCCCCHHHHHH		20.8627097102
557Asymmetric dimethylarginineIMAPPGGRSNITSLS
HHCCCCCCCCCCCCC		32.23-
561PhosphorylationPGGRSNITSLS----
CCCCCCCCCCC----		28.0628551015
562PhosphorylationGGRSNITSLS-----
CCCCCCCCCC-----		23.8728551015
564PhosphorylationRSNITSLS-------
CCCCCCCC-------		37.6328551015
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DPYL4_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DPYL4_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DPYL4_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of DPYL4_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DPYL4_RAT

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Related Literatures of Post-Translational Modification

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