dbPTM

DONS_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DONS_DROME
UniProt AC	Q9VNA8
Protein Name	Protein downstream neighbor of son homolog
Gene Name	hd
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	568
Subcellular Localization	Nucleus .
Protein Description	Essential for DNA amplification in the ovary and required for cell proliferation during development..
Protein Sequence	MSTEASVASKWTRPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKSKLLEAKLAQKRKNPFAKSTADAKKLRVDPQLADLEPVVTASSCFVRETPTRPAPAKFVLQKYDPQAFAKLFQHPQINAEDEDDAELAARQKHTAHLPVDWSLKTRARFFCPTELPAIQLKTSQLASGLTSFVRCMDPQRTESTLDISDATRFNQCNYYWQHPHLPWLTLYPRTAKENVGVVVGERERKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRPESHALVTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQEDEDDDEDWLESLGVDERELRRIQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNAKSAISTVGRLAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGVDYFSIDIKGLILPTFLPSVAELLSETRQMFSSTLASSINTLAFSKATQKLLETPETPQSDAEGEDAAGQVFGEQNLSECGLLPAVVGSICRTGQHAVGLLERVCYQRDEGYAWS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
310	Phosphorylation	RQEGIEFSMPLKSDN HHCCCEEECCCCCCC	13.50	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DONS_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DONS_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DONS_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DONS_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DONS_DROME

Related Literatures of Post-Translational Modification