DMRTD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DMRTD_HUMAN
• UniProt AC: Q8IXT2
• Protein Name: Doublesex- and mab-3-related transcription factor C2
• Gene Name: DMRTC2
• Organism: Homo sapiens (Human).
• Sequence Length: 367
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in sexual development..
• Protein Sequence: MEPSDMPAGYHCPLDSAPWDETRDPQSTELIPRRAISRSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQEAQLKKHLMRRGEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVALHIGRLGSISLLS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
117	Phosphorylation	PNHFRKGTTQPQVPS CCCCCCCCCCCCCCC	25.87	24114839
118	Phosphorylation	NHFRKGTTQPQVPSG CCCCCCCCCCCCCCC	47.09	24114839
124	Phosphorylation	TTQPQVPSGKENIAP CCCCCCCCCCCCCCC	64.74	-
145	Phosphorylation	GAVLLAPTPPGKNSC CEEEECCCCCCCCCC	36.19	30266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DMRTD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DMRTD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DMRTD_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRXR1_HUMAN	TXNRD1	physical	21988832

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.