dbPTM

DML1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DML1_SCHPO
UniProt AC	Q9P6K5
Protein Name	Protein dml1
Gene Name	dml1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	465
Subcellular Localization	Mitochondrion.
Protein Description	Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance..
Protein Sequence	MHEILTVTFGRKSNFCWTHFWNTQESYFVYDPNDHAKVNVNTNFRVLKKRDPEAIVTVPRECIYDTPIEFGNTRKNWLEELNESSGGKGTAWDGKLTQIMQTPVDVHPYQEALWSRDEIHEGNAIESEYELPSIRPKSVKYWSDFNRLFLDTEYLFPVNCSELNSSDFSFQLGVERFHDFDKQFNVWDEGLRPLVEECDSVQGFQAAIDIDTPWGGFASEYMKVVQDELGECRVPTWVYGIREPIQSDSSATIDNHFGKLNEALSLSQLNGSCSQYFPLCTISQGDDLWASSAKINLAIESFTLPTRVYGSSCYRMKDIESKLQSEGRGFIHNLNFKAKNYSSKEWALVSSASFVNVAQDYSQQNNCLFGVVRSPKDNQGLLEGKNYNASSISKIVNIQNLGLPSLETVPEGLRTLDTVFVEATNDGQINSHIQGLTKSLNRRFVSFVDQDELEEIREILSSYII

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
84	Phosphorylation	WLEELNESSGGKGTA HHHHHHHHCCCCCCC	32.96	21712547
446	Phosphorylation	SLNRRFVSFVDQDEL HHHHHHHHCCCHHHH	19.48	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DML1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DML1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DML1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DML1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DML1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-446, AND MASSSPECTROMETRY.	18257517 [Abstract]