dbPTM

DJB11_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DJB11_MOUSE
UniProt AC	Q99KV1
Protein Name	DnaJ homolog subfamily B member 11
Gene Name	Dnajb11
Organism	Mus musculus (Mouse).
Sequence Length	358
Subcellular Localization	Endoplasmic reticulum lumen .
Protein Description	Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity (By similarity)..
Protein Sequence	MAPQNLSTFCLLLLYLIGTVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHRIFERRGDDLYTNVTVSLVEALVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAKEGIKQLLKQGPVQKVYNGLQGY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Ubiquitination	IAGRDFYKILGVPRS HHCCCHHHHHCCCCC	31.29	22790023
37	Phosphorylation	LGVPRSASIKDIKKA HCCCCCCCHHHHHHH	31.27	27742792
39	Succinylation	VPRSASIKDIKKAYR CCCCCCHHHHHHHHH	51.40	23954790
78	Phosphorylation	GAAYEVLSDSEKRKQ HHHHHHCCCHHHHHH	44.24	26525534
188	Phosphorylation	GPGRFQMTQEVVCDE CCCCEEECEEEECCC	15.70	-
261	N-linked_Glycosylation	RGDDLYTNVTVSLVE CCCCCCCCHHHHHHH	17.57	-
288	Phosphorylation	DGHKVHISRDKITRP CCCEEEECCCCCCCC	21.39	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DJB11_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DJB11_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DJB11_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DJB11_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DJB11_MOUSE

Related Literatures of Post-Translational Modification