dbPTM

DIC_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DIC_MOUSE
UniProt AC	Q9QZD8
Protein Name	Mitochondrial dicarboxylate carrier
Gene Name	Slc25a10
Organism	Mus musculus (Mouse).
Sequence Length	287
Subcellular Localization	Mitochondrion inner membrane Multi-pass membrane protein.
Protein Description	Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane..
Protein Sequence	MAEARASRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYNKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVSSFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAMETAKLGPQAFFKGLFPAGIRLIPHTVLTFMFLEQLRKHFGIKVPTT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Acetylation	LQTQQEVKLRMTGMA HCCHHHHHHHHHCCC	29.62	23201123
68	S-palmitoylation	NGLSASLCRQMTYSL CCCCHHHHHHHHHHH	2.35	28526873
101	Acetylation	GPLPFYNKVLLGGIS CCCCCCCCHHCCCCC	23.92	23954790
141	Phosphorylation	PSQRRNYSHALDGLY HHHCCCHHHHHHHHH	13.06	-
158	Acetylation	AREESLRKLFSGATM HCHHHHHHHHCCCCC	60.21	23576753
158	Succinylation	AREESLRKLFSGATM HCHHHHHHHHCCCCC	60.21	23806337
253	Acetylation	LGPQAFFKGLFPAGI CCHHHHHCCCCCCCC	48.53	23576753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DIC_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DIC_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DIC_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DIC_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DIC_MOUSE

Related Literatures of Post-Translational Modification