DHR12_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DHR12_HUMAN
• UniProt AC: A0PJE2
• Protein Name: Dehydrogenase/reductase SDR family member 12
• Gene Name: DHRS12
• Organism: Homo sapiens (Human).
• Sequence Length: 317
• Protein Description: Putative oxidoreductase..
• Protein Sequence: MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATASSSPAEEEKLIEILEQLAQTFK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSLYRSVVW ------CCHHHHHHH	33.82	30631047
6	Phosphorylation	--MSLYRSVVWFAKG --CCHHHHHHHHHHH	13.89	30631047
263 (in isoform 3)	Phosphorylation	-	3.53	30631047
267 (in isoform 3)	Phosphorylation	-	3.78	30631047

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DHR12_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DHR12_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DHR12_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of DHR12_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.