DENR_MOUSE - dbPTM
DENR_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DENR_MOUSE
UniProt AC Q9CQJ6
Protein Name Density-regulated protein
Gene Name Denr
Organism Mus musculus (Mouse).
Sequence Length 198
Subcellular Localization
Protein Description May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity)..
Protein Sequence MATDISESSGADCKGDTKNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MATDISESS
------CCCCCHHCC
17.61-
6Phosphorylation--MATDISESSGADC
--CCCCCHHCCCCCC
33.9524759943
8PhosphorylationMATDISESSGADCKG
CCCCCHHCCCCCCCC
27.5529472430
9PhosphorylationATDISESSGADCKGD
CCCCHHCCCCCCCCC
33.6725266776
20PhosphorylationCKGDTKNSAKLDADY
CCCCCCCCCCCCCCC
28.47-
37S-palmitoylationRVLYCGVCSLPTEYC
EEEEEECCCCCHHHH
1.7828680068
69PhosphorylationPNEFAKLTVENSPKQ
CCHHHHEEEECCCCC
25.6825521595
73PhosphorylationAKLTVENSPKQETGI
HHEEEECCCCCCCCC
21.7025521595
78PhosphorylationENSPKQETGITEGQG
ECCCCCCCCCCCCCC
31.2425521595
81PhosphorylationPKQETGITEGQGPVG
CCCCCCCCCCCCCCC
35.0924925903
189PhosphorylationWPEVDDDSIEDLGEV
CCCCCCCCCHHHHCC
34.5722817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DENR_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DENR_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DENR_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of DENR_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DENR_MOUSE

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Related Literatures of Post-Translational Modification

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