DEC13_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DEC13_DROME
• UniProt AC: P18171
• Protein Name: Defective chorion-1 protein, FC177 isoform
• Gene Name: 1-Dec
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 1590
• Subcellular Localization: Secreted .
• Protein Description: Required for proper assembly of the eggshell..
• Protein Sequence: MRLFSLLPLLALLVVQAAGQSEVTSDDPATDAGSTTNSTTDTKPRIPSQDEILGQMPSINPIRTGNPQMDAFYMMFPALGSLLKWGSLFPAYSILGAIPDNLQPTAAASKVVLVLADDATAKTRVARQNPPPNPLGQLMNWPALPQDFQLPSMDLGPQVGSFLAQLPAMPTVPGLLGAAAPVPAPAPAPAAAPPPAPAPAADPPAAPVPDAPQPAILGQAALQNAFTFFNPANFDASSLLGQSVPTFAPPNLDFVAQMQRQFFPGMTPAQPAAAGTDAQASDISEVRVRPEDPYSQEAQMKIKSALEMEQERQQQAQVKDQEQVPLLWFRMPTTQNQDATEEKTLEDLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSAAAQNGDSPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRARNSGINTQKANALKRQAKSQDQTLSKEDIVQIMAYAYRMANEQMESEKGKQDKVYAAYRTEQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMVQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQHDQQMAQQMAQQGLMMTEQRQRQWSEDQAKIQQAQQMAQQTPMMMPQMQQRQWTEDPQMVQQMQQRQWAEDQTRMQMAQQNPMMQQQRQMAENPQMMQQRQWSEEQTKIEQAQQMAQQNQMMMQQMQQRQWSEDQAQIQQQQRQMMQQTPMMMKERQWAEENPQSVQQQGPMMMQQQMPSMMQREVEDEDNKAEDDLVGEAGPQMPENEGTARHKVDALGVGGNKRKKSKSKSAPPTVINYYYAAPQRPVVQSYGTSYGGGGYGSNAYGVPRPVNSYQSQGYRAAVGNDEVDEMLRQHQTMARTINPKQPGEVGGSESQKSNSNPPTTLTPAPQEQPQEHRVHKRLAHFHRFGREAGLNATTSKGCGCGRLDCLCGRSCRCGRRGLESRVVSSRTSGTCQCKASHRNKRSVEYGTLETIDEGSLNELRREYKLGLKEITLSPDEDPAEALMRYNAASIREALERASMEPLEIGGDQYEEDAQQEPMEEEQLQHDPNTEPQYNHKDFVRLTTSTASPITSTTEAATPTGSDSTSEATVTPEVTTTTSTSTTTTTESTKDEGLDMQQDSQAEAESSHVTKSISKQEAEIHQLHSIVEELKNEILKLNLRCSTIISNNVAKEPVTEKNPPVVEEPSKQEDKPKVEEKVIAEEQAPVEQEEELEEDEDSTSISTTTETPSPSGSYSTKPGLSLGSPRVDEQSGSSNKLDYDDDNNWQRILANRGYDTDYLTKSHERQFAQGQNLEMPKNCNYDGNGSQEYGPYPEFQADEPSTDTEGKAKRALSVKQQAQLLNAALNDSGSDSSDGTTTTTTPSPYAMRGKFVRRRSTARRVPIPKIGKASDEVWVRSPRQAKMPQRPKKSMSKPKKQSSQVTTQATVSSTKLDSLVDVLKDLVRLQIQKEKKSSLLRTQSNNLSKTKPKSIKPVKVIKRKRLRRRQHKSIATTIRSPIQTKA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
295	Phosphorylation	VRPEDPYSQEAQMKI ECCCCCCCHHHHHHH	27.25	30478224
504	Phosphorylation	MMQQRQWSEEQAKIQ HHHHHHHHHHHHHHH	23.94	30478224
530	Phosphorylation	MMQQRQWSEEQAKIQ HHHHHHHHHHHHHHH	23.94	30478224
556	Phosphorylation	MMQQRQWSEEQAKIQ HHHHHHHHHHHHHHH	23.94	30478224
582	Phosphorylation	MMQQRQWSEEQAKIQ HHHHHHHHHHHHHHH	23.94	30478224
608	Phosphorylation	MVQQRQWSEEQAKIQ HHHHHHHCHHHHHHH	23.94	30478224
634	Phosphorylation	MMQQRQWSEEQAKIQ HHHHHHHCHHHHHHH	23.94	30478224

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DEC13_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DEC13_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DEC13_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of DEC13_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.