DEAH5_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DEAH5_ARATH
• UniProt AC: Q38953
• Protein Name: Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5 {ECO:0000305}
• Gene Name: At3g26560 {ECO:0000312|Araport:AT3G26560}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1168
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in pre-mRNA splicing..
• Protein Sequence: MEKEELNKLNHLSLVSNVCNELETHLGSAEKVLAEFIIDLGRHSETVDEFDKNLKEAGAEMPDYFVRSLLTTIHGIYPPKPKSEKKKEEGDDQKFKGLAIKDTKDKVKELEKEIEREAEERRREEDRNRDRDRRESGRDRDRDRNRDRDDRRDRHRDRERNRGDEEGEDRRSDRRHRERGRGDGGEGEDRRRDRRAKDEYVEEDKGGANEPELYQVYKGRVTRVMDAGCFVQFDKFRGKEGLVHVSQMATRRVDKAKEFVKRDMEVYVKVISISSDKYSLSMRDVDQNTGRDLIPLRKPSDEDDSSRSNPSYRTKDGQVTKTGISGIRIVEENDVAPSRRPLKKMSSPERWEAKQLIASGVLRVDEFPMYDEDGDGMLYQEEGAEEELEIEMNEDEPAFLQGQTRYSVDMSPVKIFKNPEGSLSRAAALQSALTKERREMREQQQRTMLDSIPKDLNRPWEDPMPETGERHLAQELRGVGLSAYDMPEWKKDAFGKTPTFGQRSKLSIQEQRESLPIYKLKKELIQAVHDNQVLVVIGETGSGKTTQVTQYLAEAGYTTKGKIGCTQPRRVAAMSVAKRVAEEFGCRLGEEVGYAIRFEDCTGPDTVIKYMTDGMLLREILIDENLSQYSVIMLDEAHERTIHTDVLFGLLKKLMKRRLDLRLIVTSATLDAEKFSGYFFNCNIFTIPGRTFPVEILYTKQPETDYLDAALITVLQIHLTEPEGDILVFLTGQEEIDSACQSLYERMKGLGKNVPELIILPVYSALPSEMQSRIFDPPPPGKRKVVVATNIAEASLTIDGIYYVVDPGFAKQNVYNPKQGLESLVITPISQASAKQRAGRAGRTGPGKCYRLYTESAYRNEMPPTSIPEIQRINLGMTTLTMKAMGINDLLSFDFMDPPQPQALISAMEQLYSLGALDEEGLLTKLGRKMAEFPLEPPLSKMLLASVDLGCSDEILTMIAMIQTGNIFYRPREKQAQADQKRAKFFQPEGDHLTLLAVYEAWKAKNFSGPWCFENFIQSRSLRRAQDVRKQLLSIMDKYKLDVVTAGKNFTKIRKAITAGFFFHGARKDPQEGYRTLVENQPVYIHPSSALFQRQPDWVIYHDLVMTTKEYMREVTVIDPKWLVELAPRFFKVSDPTKMSKRKRQERIEPLYDRYHEPNSWRLSKRRA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
267	Phosphorylation	VKRDMEVYVKVISIS HHHHCEEEEEEEEEC		23660473
272	Phosphorylation	EVYVKVISISSDKYS EEEEEEEEECCCCCE		23660473
274	Phosphorylation	YVKVISISSDKYSLS EEEEEEECCCCCEEE		23660473
275	Phosphorylation	VKVISISSDKYSLSM EEEEEECCCCCEEEC		23660473
278	Phosphorylation	ISISSDKYSLSMRDV EEECCCCCEEECCCC		23660473
279	Phosphorylation	SISSDKYSLSMRDVD EECCCCCEEECCCCC		23660473
281	Phosphorylation	SSDKYSLSMRDVDQN CCCCCEEECCCCCCC		23660473
300	Phosphorylation	LIPLRKPSDEDDSSR CEECCCCCCCCCCCC		25561503
346	Phosphorylation	RRPLKKMSSPERWEA CCCCCCCCCHHHHHH		23776212
347	Phosphorylation	RPLKKMSSPERWEAK CCCCCCCCHHHHHHH		19880383
406	Phosphorylation	FLQGQTRYSVDMSPV HHCCCEEEEECCCCE		23172892
407	Phosphorylation	LQGQTRYSVDMSPVK HCCCEEEEECCCCEE		23172892
411	Phosphorylation	TRYSVDMSPVKIFKN EEEEECCCCEEEECC		30291188
422	Phosphorylation	IFKNPEGSLSRAAAL EECCCCCCHHHHHHH		25368622
424	Phosphorylation	KNPEGSLSRAAALQS CCCCCCHHHHHHHHH		25368622
505	Sumoylation	PTFGQRSKLSIQEQR CCCCHHHCCCHHHHH		-
666	Phosphorylation	LDLRLIVTSATLDAE CCCEEEEEECCCCHH		19880383
667	Phosphorylation	DLRLIVTSATLDAEK CCEEEEEECCCCHHH		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DEAH5_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DEAH5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DEAH5_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of DEAH5_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.