DDX56_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DDX56_MOUSE
• UniProt AC: Q9D0R4
• Protein Name: Probable ATP-dependent RNA helicase DDX56
• Gene Name: Ddx56
• Organism: Mus musculus (Mouse).
• Sequence Length: 546
• Subcellular Localization: Nucleus, nucleolus.
• Protein Description: May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity (By similarity)..
• Protein Sequence: MEDQEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQSLLHKKATGPVMEQAVRGLVLVPTKELARQAQAMIQQLAAYCARDVRVANVSAAEDSASQRAVLMEKPDVVVGTPSRVLSHLQQNTLKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLPRIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATDAEILGPQVKGKRRGRGSKGNKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPAEQPFLGKIEDLLSGEGEAPILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPAALRGLVHPRKKRRKVPFSRKAKKVKAQNPLRDFKHRGKKPKPAAKPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
75	Phosphorylation	SLLHKKATGPVMEQA HHHHHHCCCHHHHHH	51.39	-
124	Phosphorylation	NVSAAEDSASQRAVL CCCHHCCCHHHHHHH	22.71	27566939
126	Phosphorylation	SAAEDSASQRAVLME CHHCCCHHHHHHHHC	24.93	-
141	Phosphorylation	KPDVVVGTPSRVLSH CCCEEEECHHHHHHH	13.38	-
143	Phosphorylation	DVVVGTPSRVLSHLQ CEEEECHHHHHHHHH	34.55	-
147	Phosphorylation	GTPSRVLSHLQQNTL ECHHHHHHHHHHCCC	21.21	-
153	Phosphorylation	LSHLQQNTLKLRDSL HHHHHHCCCHHHHCE	22.41	-
334	Methylation	KRRGRGSKGNKASDP CCCCCCCCCCCCCCC	70.13	-
337	Methylation	GRGSKGNKASDPESG CCCCCCCCCCCCCCC	58.92	-
457	Phosphorylation	IKEELLHSEKLKTYF HHHHHHCCHHHHHHH	36.07	29472430

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DDX56_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DDX56_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DDX56_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of DDX56_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.