dbPTM

DDX52_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DDX52_MOUSE
UniProt AC	Q8K301
Protein Name	Probable ATP-dependent RNA helicase DDX52
Gene Name	Ddx52
Organism	Mus musculus (Mouse).
Sequence Length	598
Subcellular Localization	Nucleus, nucleolus.
Protein Description
Protein Sequence	MDSYDLFRRLGAGAKFDVKRFSADATRFQVGKRKFDSESLEVLKGLDFFGNKKSVSDECGALQIHQEPPNEEKTQGVLLERSKEPKKKKRKKMTSEVPAQEDFDGGIQWTSSVEAKLQDEKVSGEKKLTSGKLEHLRKEKVNFFRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQVPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPTNKGFRALVISPTRELASQIHRELIKISEGTGFRIHMIHKAAIAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLTNVEWLVVDESDKLFEDGKTGFREQLASIFLACTSPKVRRAMFSATFAYDVEQWCKLNLDNVVSVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFKPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNRGKAVTFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESICTTPKYFLEQAKQKKVAGQNSKKKETLKEKS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Acetylation	RRLGAGAKFDVKRFS HHHCCCCCCEEEEEC	40.97	-
22	Phosphorylation	KFDVKRFSADATRFQ CCEEEEECCCCCEEE	29.31	29176673
39	Phosphorylation	KRKFDSESLEVLKGL CCCCCHHHHHHHHCC	33.51	29514104
579	Acetylation	KYFLEQAKQKKVAGQ HHHHHHHHHHHHCCC	63.44	8276593
582	Acetylation	LEQAKQKKVAGQNSK HHHHHHHHHCCCCHH	34.52	8276603
591	Acetylation	AGQNSKKKETLKEKS CCCCHHHHHHHHHCC	60.72	8276613

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DDX52_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DDX52_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DDX52_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DDX52_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DDX52_MOUSE

Related Literatures of Post-Translational Modification