dbPTM

DDX1_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DDX1_DROME
UniProt AC	Q9VNV3
Protein Name	ATP-dependent RNA helicase Ddx1
Gene Name	Ddx1
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	727
Subcellular Localization
Protein Description	Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity (By similarity)..
Protein Sequence	MTAFEEFGVLPELGMATDELDWTLPTDVQAEAIPLILGGGDVLMAAETGSGKTGAFCLPILQIVWETLRDLEEGKAGKGGAIGGAVTPWTMSFFDRGNALAVTPDGLRCQSREFKEWHGCRATTGVRGKGKFYFEATVTDEGLCRVGWSTQQANLDLGTCRMGFGFGGTGKKSNNRQFDDYGEAFGKADVIGCLLDLKNQEVSFTKNGQNLGVAFRLPDNLAKETFYPAVVLKNAEMQFNFGKTDFKYAPGNGFVGACQAGPEHSKANPITGPAAGAPSAKPAPNAPQAIIMEPSRELAEQTYNQIEKFKYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGRLEEMINSGLVLLTHCRFFVLDEADALLKQGYTELIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGEDAVPETVHHVVCLVDPQMDTTWQSLRQPIGTDGVHDRDNVHPGNHSKETLSQAVKLLKGEYCVHAIDKHNMDRAIIFCRTKQDCDNLERFLRQRGGKHYSCVCLHGDRKPQERKENLEMFKRQQVKFLICTDVAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISLVATVPEKVWYHGEWCKSRGRSCNNTNLTEVRGCCIWYNEPNLLAEVEDHLNITIQQVDKTMDVPVNDFDGKVVYGQKNLRTGSGYEDHVEQLVPTVRKLTELELQSQSLFLKRLKV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
531	Acetylation	FLRQRGGKHYSCVCL HHHHCCCCCEEEEEE	42.04	21791702
711	Phosphorylation	VPTVRKLTELELQSQ HHHHHHHHHHHHHHH	41.37	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DDX1_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DDX1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DDX1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DDX1_DROME

Related Literatures of Post-Translational Modification